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Page 1
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
Londregan AT, Aitmakhanova K, Bennett J, Byrnes LJ, Canterbury DP, Cheng X, Christott T, Clemens J, Coffey SB, Dias JM, Dowling MS, Farnie G, Fedorov O, Fennell KF, Gamble V, Gileadi C, Giroud C, Harris MR, Hollingshead BD, Huber K, Korczynska M, Lapham K, Loria PM, Narayanan A, Owen DR, Raux B, Sahasrabudhe PV, Ruggeri RB, Sáez LD, Stock IA, Thuma BA, Tsai A, Varghese AE. Londregan AT, et al. Among authors: korczynska m. J Med Chem. 2023 Jan 12;66(1):460-472. doi: 10.1021/acs.jmedchem.2c01421. Epub 2022 Dec 23. J Med Chem. 2023. PMID: 36562986
Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3.
Raux B, Buchan KA, Bennett J, Christott T, Dowling MS, Farnie G, Fedorov O, Gamble V, Gileadi C, Giroud C, Huber KVM, Korczynska M, Limberakis C, Narayanan A, Owen DR, Sáez LD, Stock IA, Londregan AT. Raux B, et al. Among authors: korczynska m. Bioorg Med Chem Lett. 2024 Jan 15;98:129546. doi: 10.1016/j.bmcl.2023.129546. Epub 2023 Nov 7. Bioorg Med Chem Lett. 2024. PMID: 37944866
Analysis of the impact of sex and age on the variation in the prevalence of antinuclear autoantibodies in Polish population: a nationwide observational, cross-sectional study.
Krzemień P, Kasperczyk S, Banach M, Kasperczyk A, Dobrakowski M, Tomasik T, Windak A, Mastej M, Catapano A, Ray KK, Mikhailidis DP, Toth PP, Howard G, Lip GYH, Tomaszewski M, Charchar FJ, Sattar N, Williams B, MacDonald TM, Penson PE, Jóźwiak JJ; LIPIDOGRAM2015 Investigators. Krzemień P, et al. Rheumatol Int. 2022 Feb;42(2):261-271. doi: 10.1007/s00296-021-05033-9. Epub 2021 Nov 10. Rheumatol Int. 2022. PMID: 34755204 Free PMC article.
An allosteric modulator binds to a conformational hub in the β2 adrenergic receptor.
Liu X, Kaindl J, Korczynska M, Stößel A, Dengler D, Stanek M, Hübner H, Clark MJ, Mahoney J, Matt RA, Xu X, Hirata K, Shoichet BK, Sunahara RK, Kobilka BK, Gmeiner P. Liu X, et al. Among authors: korczynska m. Nat Chem Biol. 2020 Jul;16(7):749-755. doi: 10.1038/s41589-020-0549-2. Epub 2020 Jun 1. Nat Chem Biol. 2020. PMID: 32483378 Free PMC article.
The Recognition of Unrelated Ligands by Identical Proteins.
Pottel J, Levit A, Korczynska M, Fischer M, Shoichet BK. Pottel J, et al. Among authors: korczynska m. ACS Chem Biol. 2018 Sep 21;13(9):2522-2533. doi: 10.1021/acschembio.8b00443. Epub 2018 Aug 27. ACS Chem Biol. 2018. PMID: 30095890 Free PMC article.
A two fatal cases of poisoning involving new cathinone derivative PV8.
Pieprzyca E, Skowronek R, Korczyńska M, Kulikowska J, Chowaniec M. Pieprzyca E, et al. Among authors: korczynska m. Leg Med (Tokyo). 2018 May 14;33:42-47. doi: 10.1016/j.legalmed.2018.05.002. Online ahead of print. Leg Med (Tokyo). 2018. PMID: 29778973
Exploring the effect of previous inactivated influenza vaccination on seasonal influenza vaccine effectiveness against medically attended influenza: Results of the European I-MOVE multicentre test-negative case-control study, 2011/2012-2016/2017.
Valenciano M, Kissling E, Larrauri A, Nunes B, Pitigoi D, O'Donnell J, Reuss A, Horváth JK, Paradowska-Stankiewicz I, Rizzo C, Falchi A, Daviaud I, Brytting M, Meijer A, Kaic B, Gherasim A, Machado A, Ivanciuc A, Domegan L, Schweiger B, Ferenczi A, Korczyńska M, Bella A, Vilcu AM, Mosnier A, Zakikhany K, de Lange M, Kurečić Filipovićović S, Johansen K, Moren A; I-MOVE primary care multicentre case-control team. Valenciano M, et al. Among authors: korczynska m. Influenza Other Respir Viruses. 2018 Sep;12(5):567-581. doi: 10.1111/irv.12562. Epub 2018 May 9. Influenza Other Respir Viruses. 2018. PMID: 29659149 Free PMC article.
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor.
Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, Christopoulos A, Shoichet BK, Sunahara RK. Korczynska M, et al. Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2419-E2428. doi: 10.1073/pnas.1718037115. Epub 2018 Feb 16. Proc Natl Acad Sci U S A. 2018. PMID: 29453275 Free PMC article.
40 results