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Improving the efficiency and effectiveness of an industrial SARS-CoV-2 diagnostic facility.
Sci Rep. 2022 Feb 24;12(1):3114. doi: 10.1038/s41598-022-06873-6.
Sci Rep. 2022.
PMID: 35210470
Free PMC article.
Pharmacological validation of targets regulating CD14 during macrophage differentiation.
Jimenez-Duran G, Luque-Martin R, Patel M, Koppe E, Bernard S, Sharp C, Buchan N, Rea C, de Winther MPJ, Turan N, Angell D, Wells CA, Cousins R, Mander PK, Masters SL.
Jimenez-Duran G, et al.
EBioMedicine. 2020 Nov;61:103039. doi: 10.1016/j.ebiom.2020.103039. Epub 2020 Oct 7.
EBioMedicine. 2020.
PMID: 33038762
Free PMC article.
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Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages.
Triantafilou K, Ward CJK, Czubala M, Ferris RG, Koppe E, Haffner C, Piguet V, Patel VK, Amrine-Madsen H, Modis LK, Masters SL, Triantafilou M.
Triantafilou K, et al.
PLoS Pathog. 2021 Apr 16;17(4):e1009417. doi: 10.1371/journal.ppat.1009417. eCollection 2021 Apr.
PLoS Pathog. 2021.
PMID: 33861800
Free PMC article.
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Human rhinovirus promotes STING trafficking to replication organelles to promote viral replication.
Triantafilou M, Ramanjulu J, Booty LM, Jimenez-Duran G, Keles H, Saunders K, Nevins N, Koppe E, Modis LK, Pesiridis GS, Bertin J, Triantafilou K.
Triantafilou M, et al.
Nat Commun. 2022 Mar 17;13(1):1406. doi: 10.1038/s41467-022-28745-3.
Nat Commun. 2022.
PMID: 35301296
Free PMC article.
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An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation.
Carroll RG, Zasłona Z, Galván-Peña S, Koppe EL, Sévin DC, Angiari S, Triantafilou M, Triantafilou K, Modis LK, O'Neill LA.
Carroll RG, et al. Among authors: koppe el.
J Biol Chem. 2018 Apr 13;293(15):5509-5521. doi: 10.1074/jbc.RA118.001921. Epub 2018 Feb 20.
J Biol Chem. 2018.
PMID: 29463677
Free PMC article.
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Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren's syndrome is associated with B cell hyperactivity and type I interferon activity.
Hillen MR, Urso K, Koppe E, Lopes AP, Blokland SLM, Pandit A, Slocombe T, van Maurik A, van Roon JAG, Radstake TRDJ.
Hillen MR, et al.
RMD Open. 2020 Jun;6(2):e001184. doi: 10.1136/rmdopen-2020-001184.
RMD Open. 2020.
PMID: 32540951
Free PMC article.
No abstract available.
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In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization.
Kamola PJ, Kitson JD, Turner G, Maratou K, Eriksson S, Panjwani A, Warnock LC, Douillard Guilloux GA, Moores K, Koppe EL, Wixted WE, Wilson PA, Gooderham NJ, Gant TW, Clark KL, Hughes SA, Edbrooke MR, Parry JD.
Kamola PJ, et al. Among authors: koppe el.
Nucleic Acids Res. 2015 Oct 15;43(18):8638-50. doi: 10.1093/nar/gkv857. Epub 2015 Sep 3.
Nucleic Acids Res. 2015.
PMID: 26338776
Free PMC article.
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The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.
D'Alessandro PL, Corti C, Roth A, Ugolini A, Sava A, Montanari D, Bianchi F, Garland SL, Powney B, Koppe EL, Rocheville M, Osborne G, Perez P, de la Fuente J, De Los Frailes M, Smith PW, Branch C, Nash D, Watson SP.
D'Alessandro PL, et al. Among authors: koppe el.
Bioorg Med Chem Lett. 2010 Jan 15;20(2):759-62. doi: 10.1016/j.bmcl.2009.11.032. Epub 2009 Nov 26.
Bioorg Med Chem Lett. 2010.
PMID: 20005096
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