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Multi-ancestry genome-wide association study of asthma exacerbations.
Herrera-Luis E, Ortega VE, Ampleford EJ, Sio YY, Granell R, de Roos E, Terzikhan N, Vergara EE, Hernandez-Pacheco N, Perez-Garcia J, Martin-Gonzalez E, Lorenzo-Diaz F, Hashimoto S, Brinkman P; U-BIOPRED Study Group; Jorgensen AL, Yan Q, Forno E, Vijverberg SJ, Lethem R, Espuela-Ortiz A, Gorenjak M, Eng C, González-Pérez R, Hernández-Pérez JM, Poza-Guedes P, Sardón O, Corcuera P, Hawkins GA, Marsico A, Bahmer T, Rabe KF, Hansen G, Kopp MV, Rios R, Cruz MJ, González-Barcala FJ, Olaguibel JM, Plaza V, Quirce S, Canino G, Cloutier M, Del Pozo V, Rodriguez-Santana JR, Korta-Murua J, Villar J, Potočnik U, Figueiredo C, Kabesch M, Mukhopadhyay S, Pirmohamed M, Hawcutt DB, Melén E, Palmer CN, Turner S, Maitland-van der Zee AH, von Mutius E, Celedón JC, Brusselle G, Chew FT, Bleecker E, Meyers D, Burchard EG, Pino-Yanes M. Herrera-Luis E, et al. Among authors: kopp mv. Pediatr Allergy Immunol. 2022 Jun;33(6):e13802. doi: 10.1111/pai.13802. Pediatr Allergy Immunol. 2022. PMID: 35754128 Free PMC article.
The Relevance of Small Airway Dysfunction in Asthma with Nocturnal Symptoms.
Abdo M, Trinkmann F, Kirsten AM, Biller H, Pedersen F, Waschki B, Von Mutius E, Kopp M, Hansen G, Rabe KF, Bahmer T, Watz H; ALLIANCE study group. Abdo M, et al. Among authors: kopp m. J Asthma Allergy. 2021 Jul 13;14:897-905. doi: 10.2147/JAA.S313572. eCollection 2021. J Asthma Allergy. 2021. PMID: 34285516 Free PMC article.
Longitudinal Impact of Sputum Inflammatory Phenotypes on Small Airway Dysfunction and Disease Outcomes in Asthma.
Abdo M, Pedersen F, Kirsten AM, Veith V, Biller H, Trinkmann F, von Mutius E, Kopp M, Hansen G, Rabe KF, Bahmer T, Watz H; ALLIANCE study group. Abdo M, et al. Among authors: kopp m. J Allergy Clin Immunol Pract. 2022 Jun;10(6):1545-1553.e2. doi: 10.1016/j.jaip.2022.02.020. Epub 2022 Mar 5. J Allergy Clin Immunol Pract. 2022. PMID: 35257957 Free article.
Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma.
Abdo M, Uddin M, Goldmann T, Marwitz S, Bahmer T, Holz O, Kirsten AM, Trinkmann F, von Mutius E, Kopp M, Hansen G, Rabe KF, Watz H, Pedersen F; ALLIANCE study group. Abdo M, et al. Among authors: kopp m. Respir Res. 2021 Jun 3;22(1):167. doi: 10.1186/s12931-021-01759-z. Respir Res. 2021. PMID: 34082773 Free PMC article.
A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype.
Rønnow SR, Sand JMB, Staunstrup LM, Bahmer T, Wegmann M, Lunding L, Burgess J, Rabe K, Sorensen GL, Fuchs O, Mutius EV, Hansen G, Kopp MV, Karsdal M, Leeming DJ, Weckmann M; ALLIANCE Study Group as part of the German Center of Lung Research (DZL). Rønnow SR, et al. Among authors: kopp mv. Asthma Res Pract. 2022 Apr 13;8(1):2. doi: 10.1186/s40733-022-00084-6. Asthma Res Pract. 2022. PMID: 35418159 Free PMC article.
COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy.
Weckmann M, Bahmer T, Sand JM, Rank Rønnow S, Pech M, Vermeulen C, Faiz A, Leeming DJ, Karsdal MA, Lunding L, Oliver BGG, Wegmann M, Ulrich-Merzenich G, Juergens UR, Duhn J, Laumonnier Y, Danov O, Sewald K, Zissler U, Jonker M, König I, Hansen G, von Mutius E, Fuchs O, Dittrich AM, Schaub B, Happle C, Rabe KF, van de Berge M, Burgess JK, Kopp MV; ALLIANCE Study Group as part of the German Centre for Lung Research (DZL). Weckmann M, et al. Among authors: kopp mv. Eur Respir J. 2021 Dec 9;58(6):2003969. doi: 10.1183/13993003.03969-2020. Print 2021 Dec. Eur Respir J. 2021. PMID: 34326188 Free article.
IgA+ memory B-cells are significantly increased in patients with asthma and small airway dysfunction.
Habener A, Grychtol R, Gaedcke S, DeLuca D, Dittrich AM, Happle C, Abdo M, Watz H, Pedersen F, König IR, Thiele D, Kopp MV, von Mutius E, Bahmer T, Rabe KF, Meyer-Bahlburg A, Hansen G; ALLIANCE Study Group as part of the German Center for Lung Research (DZL); Fuchs O, Roesler B, Welchering N, Kohistani-Greif N, Kurz J, Landgraf-Rauf K, Laubhahn K, Maison N, Liebl C, Schaub B, Ege M, Illi S, Hose A, Zeitlmann E, Berbig M, Marzi C, Schauberger C, Zissler U, Schmidt-Weber C, Ricklefs I, Diekmann G, Liboschik L, Voigt G, Sultansei L, Weckmann M, Nissen G, Kirsten AM, Waschki B, Herzmann C, Biller H, Gaede KI, Bovermann X, Steinmetz A, Husstedt BL, Nitsche C, Veith V, Szewczyk M, Brinkmann F, Malik A, Schwerk N, Dopfer C, Price M, Jirmo AC, Liu B, Calveron MR, Weber S, Foth S, Skevaki C, Renz H, Meyer M, Schildberg T, Rietschel E, van Koningsbruggen-Rietschel S, Alcazar M. Habener A, et al. Among authors: kopp mv. Eur Respir J. 2022 Nov 3;60(5):2102130. doi: 10.1183/13993003.02130-2021. Print 2022 Nov. Eur Respir J. 2022. PMID: 35595320 Free PMC article.
729 results