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AMPKα1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation.
Wang YN, Lu YX, Liu J, Jin Y, Bi HC, Zhao Q, Liu ZX, Li YQ, Hu JJ, Sheng H, Jiang YM, Zhang C, Tian F, Chen Y, Pan ZZ, Chen G, Zeng ZL, Liu KY, Ogasawara M, Yun JP, Ju HQ, Feng JX, Xie D, Gao S, Jia WH, Kopetz S, Xu RH, Wang F. Wang YN, et al. Among authors: kopetz s. Oncogene. 2020 Jan;39(3):637-650. doi: 10.1038/s41388-019-1004-2. Epub 2019 Sep 17. Oncogene. 2020. PMID: 31530934 Free PMC article.
Emerging drugs for colorectal cancer.
Fogelman DR, Kopetz S, Eng C. Fogelman DR, et al. Among authors: kopetz s. Expert Opin Emerg Drugs. 2008 Dec;13(4):629-42. doi: 10.1517/14728210802544575. Expert Opin Emerg Drugs. 2008. PMID: 19046131 Review.
Adjuvant chemotherapy with FOLFOX for primary colorectal cancer is associated with increased somatic gene mutations and inferior survival in patients undergoing hepatectomy for metachronous liver metastases.
Andreou A, Kopetz S, Maru DM, Chen SS, Zimmitti G, Brouquet A, Shindoh J, Curley SA, Garrett C, Overman MJ, Aloia TA, Vauthey JN. Andreou A, et al. Among authors: kopetz s. Ann Surg. 2012 Oct;256(4):642-50. doi: 10.1097/SLA.0b013e31826b4dcc. Ann Surg. 2012. PMID: 22968062 Free PMC article.
Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents.
Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R Jr, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Mao M, et al. Among authors: kopetz s. Clin Cancer Res. 2013 Feb 1;19(3):657-67. doi: 10.1158/1078-0432.CCR-11-1446. Epub 2012 Dec 18. Clin Cancer Res. 2013. PMID: 23251002 Free PMC article.
Clinical biomarkers in colorectal cancer.
Morris V, Kopetz S. Morris V, et al. Among authors: kopetz s. Clin Adv Hematol Oncol. 2013 Dec;11(12):768-76. Clin Adv Hematol Oncol. 2013. PMID: 24893280 Review.
444 results