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A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver.
BMC Biol. 2022 Apr 1;20(1):74. doi: 10.1186/s12915-022-01262-x.
BMC Biol. 2022.
PMID: 35361222
Free PMC article.
Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.
Imre G, Takács B, Czipa E, Drubi AB, Jaksa G, Latinovics D, Nagy A, Karkas R, Hudoba L, Vásárhelyi BM, Pankotai-Bodó G, Blastyák A, Hegedűs Z, Germán P, Bálint B, Ahmed Abdullah KS, Kopasz AG, Kovács A, Nagy LG, Sükösd F, Pintér L, Rülicke T, Barta E, Nagy I, Haracska L, Mátés L.
Imre G, et al. Among authors: kopasz ag.
Mol Ther Methods Clin Dev. 2023 Mar 14;29:145-159. doi: 10.1016/j.omtm.2023.03.003. eCollection 2023 Jun 8.
Mol Ther Methods Clin Dev. 2023.
PMID: 37025950
Free PMC article.
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