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Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Frueh L, Li Y, Mather MW, Li Q, Pou S, Nilsen A, Winter RW, Forquer IP, Pershing AM, Xie LH, Smilkstein MJ, Caridha D, Koop DR, Campbell RF, Sciotti RJ, Kreishman-Deitrick M, Kelly JX, Vesely B, Vaidya AB, Riscoe MK. Frueh L, et al. Among authors: koop dr. ACS Infect Dis. 2017 Oct 13;3(10):728-735. doi: 10.1021/acsinfecdis.7b00062. Epub 2017 Sep 27. ACS Infect Dis. 2017. PMID: 28927276 Free PMC article.
ELQ-331 as a prototype for extremely durable chemoprotection against malaria.
Smilkstein MJ, Pou S, Krollenbrock A, Bleyle LA, Dodean RA, Frueh L, Hinrichs DJ, Li Y, Martinson T, Munar MY, Winter RW, Bruzual I, Whiteside S, Nilsen A, Koop DR, Kelly JX, Kappe SHI, Wilder BK, Riscoe MK. Smilkstein MJ, et al. Among authors: koop dr. Malar J. 2019 Aug 27;18(1):291. doi: 10.1186/s12936-019-2921-9. Malar J. 2019. PMID: 31455339 Free PMC article.
Optimization of endochin-like quinolones for antimalarial activity.
Winter R, Kelly JX, Smilkstein MJ, Hinrichs D, Koop DR, Riscoe MK. Winter R, et al. Among authors: koop dr. Exp Parasitol. 2011 Feb;127(2):545-51. doi: 10.1016/j.exppara.2010.10.016. Epub 2010 Oct 30. Exp Parasitol. 2011. PMID: 21040724 Free PMC article.
Omega-hydroxylation of farnesol by mammalian cytochromes p450.
DeBarber AE, Bleyle LA, Roullet JB, Koop DR. DeBarber AE, et al. Among authors: koop dr. Biochim Biophys Acta. 2004 Jun 1;1682(1-3):18-27. doi: 10.1016/j.bbalip.2004.01.003. Biochim Biophys Acta. 2004. PMID: 15158752
125 results