Kool ET - Search Results

1

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries.

Kuljanin M, Mitchell DC, Schweppe DK, Gikandi AS, Nusinow DP, Bulloch NJ, Vinogradova EV, Wilson DL, Kool ET, Mancias JD, Cravatt BF, Gygi SP. Kuljanin M, et al. Among authors: kool et. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4. Nat Biotechnol. 2021. PMID: 33398154 Free PMC article.

2

Fluorescent Probes of DNA Repair.

Wilson DL, Kool ET. Wilson DL, et al. Among authors: kool et. ACS Chem Biol. 2018 Jul 20;13(7):1721-1733. doi: 10.1021/acschembio.7b00919. Epub 2017 Nov 30. ACS Chem Biol. 2018. PMID: 29156135 Free PMC article. Review.

3

Fluorescence Probes for ALKBH2 Allow the Measurement of DNA Alkylation Repair and Drug Resistance Responses.

Wilson DL, Beharry AA, Srivastava A, O'Connor TR, Kool ET. Wilson DL, et al. Among authors: kool et. Angew Chem Int Ed Engl. 2018 Sep 24;57(39):12896-12900. doi: 10.1002/anie.201807593. Epub 2018 Sep 3. Angew Chem Int Ed Engl. 2018. PMID: 30098084 Free PMC article.

4

Dual Inhibitors of 8-Oxoguanine Surveillance by OGG1 and NUDT1.

Tahara YK, Kietrys AM, Hebenbrock M, Lee Y, Wilson DL, Kool ET. Tahara YK, et al. Among authors: kool et. ACS Chem Biol. 2019 Dec 20;14(12):2606-2615. doi: 10.1021/acschembio.9b00490. Epub 2019 Oct 29. ACS Chem Biol. 2019. PMID: 31622553 Free PMC article.

5

Ultrafast Oxime Formation Enables Efficient Fluorescence Light-up Measurement of DNA Base Excision.

Wilson DL, Kool ET. Wilson DL, et al. Among authors: kool et. J Am Chem Soc. 2019 Dec 11;141(49):19379-19388. doi: 10.1021/jacs.9b09812. Epub 2019 Nov 27. J Am Chem Soc. 2019. PMID: 31774658 Free PMC article.

6

An Excimer Clamp for Measuring Damaged-Base Excision by the DNA Repair Enzyme NTH1.

Jun YW, Wilson DL, Kietrys AM, Lotsof ER, Conlon SG, David SS, Kool ET. Jun YW, et al. Among authors: kool et. Angew Chem Int Ed Engl. 2020 May 4;59(19):7450-7455. doi: 10.1002/anie.202001516. Epub 2020 Mar 17. Angew Chem Int Ed Engl. 2020. PMID: 32109332 Free PMC article.

7

Fluorescence Imaging of Mitochondrial DNA Base Excision Repair Reveals Dynamics of Oxidative Stress Responses.

Jun YW, Albarran E, Wilson DL, Ding J, Kool ET. Jun YW, et al. Among authors: kool et. Angew Chem Int Ed Engl. 2022 Feb 1;61(6):e202111829. doi: 10.1002/anie.202111829. Epub 2021 Dec 22. Angew Chem Int Ed Engl. 2022. PMID: 34851014 Free PMC article.

8

Efficient DNA fluorescence labeling via base excision trapping.

Jun YW, Harcourt EM, Xiao L, Wilson DL, Kool ET. Jun YW, et al. Among authors: kool et. Nat Commun. 2022 Aug 26;13(1):5043. doi: 10.1038/s41467-022-32494-8. Nat Commun. 2022. PMID: 36028479 Free PMC article.

9

Nonenzymatic autoligation in direct three-color detection of RNA and DNA point mutations.

Xu Y, Karalkar NB, Kool ET. Xu Y, et al. Among authors: kool et. Nat Biotechnol. 2001 Feb;19(2):148-52. doi: 10.1038/84414. Nat Biotechnol. 2001. PMID: 11175729

10

Epigenetics: A new methyl mark on messengers.

Kietrys AM, Kool ET. Kietrys AM, et al. Among authors: kool et. Nature. 2016 Feb 25;530(7591):423-4. doi: 10.1038/530423a. Nature. 2016. PMID: 26911777 Free PMC article.

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