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Impaired Lysosomal Integral Membrane Protein 2-dependent Peroxiredoxin 6 Delivery to Lamellar Bodies Accounts for Altered Alveolar Phospholipid Content in Adaptor Protein-3-deficient pearl Mice.
Kook S, Wang P, Young LR, Schwake M, Saftig P, Weng X, Meng Y, Neculai D, Marks MS, Gonzales L, Beers MF, Guttentag S. Kook S, et al. J Biol Chem. 2016 Apr 15;291(16):8414-27. doi: 10.1074/jbc.M116.720201. Epub 2016 Feb 23. J Biol Chem. 2016. PMID: 26907692 Free PMC article.
Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.
Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Jacob A, et al. Among authors: kook s. Cell Stem Cell. 2017 Oct 5;21(4):472-488.e10. doi: 10.1016/j.stem.2017.08.014. Epub 2017 Sep 28. Cell Stem Cell. 2017. PMID: 28965766 Free PMC article.
Successful Establishment of Primary Type II Alveolar Epithelium with 3D Organotypic Coculture.
Sucre JMS, Jetter CS, Loomans H, Williams J, Plosa EJ, Benjamin JT, Young LR, Kropski JA, Calvi CL, Kook S, Wang P, Gleaves L, Eskaros A, Goetzl L, Blackwell TS, Guttentag SH, Zijlstra A. Sucre JMS, et al. Among authors: kook s. Am J Respir Cell Mol Biol. 2018 Aug;59(2):158-166. doi: 10.1165/rcmb.2017-0442MA. Am J Respir Cell Mol Biol. 2018. PMID: 29625013 Free PMC article.
Single-Cell Transcriptomic Profiling of Pluripotent Stem Cell-Derived SCGB3A2+ Airway Epithelium.
McCauley KB, Alysandratos KD, Jacob A, Hawkins F, Caballero IS, Vedaie M, Yang W, Slovik KJ, Morley M, Carraro G, Kook S, Guttentag SH, Stripp BR, Morrisey EE, Kotton DN. McCauley KB, et al. Among authors: kook s. Stem Cell Reports. 2018 May 8;10(5):1579-1595. doi: 10.1016/j.stemcr.2018.03.013. Epub 2018 Apr 12. Stem Cell Reports. 2018. PMID: 29657097 Free PMC article.
β1 Integrin regulates adult lung alveolar epithelial cell inflammation.
Plosa EJ, Benjamin JT, Sucre JM, Gulleman PM, Gleaves LA, Han W, Kook S, Polosukhin VV, Haake SM, Guttentag SH, Young LR, Pozzi A, Blackwell TS, Zent R. Plosa EJ, et al. Among authors: kook s. JCI Insight. 2020 Jan 30;5(2):e129259. doi: 10.1172/jci.insight.129259. JCI Insight. 2020. PMID: 31873073 Free PMC article.
Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD.
Benjamin JT, Plosa EJ, Sucre JM, van der Meer R, Dave S, Gutor S, Nichols DS, Gulleman PM, Jetter CS, Han W, Xin M, Dinella PC, Catanzarite A, Kook S, Dolma K, Lal CV, Gaggar A, Blalock JE, Newcomb DC, Richmond BW, Kropski JA, Young LR, Guttentag SH, Blackwell TS. Benjamin JT, et al. Among authors: kook s. J Clin Invest. 2021 Jan 4;131(1):e139481. doi: 10.1172/JCI139481. J Clin Invest. 2021. PMID: 33108351 Free PMC article.
Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease.
Alysandratos KD, Russo SJ, Petcherski A, Taddeo EP, Acín-Pérez R, Villacorta-Martin C, Jean JC, Mulugeta S, Rodriguez LR, Blum BC, Hekman RM, Hix OT, Minakin K, Vedaie M, Kook S, Tilston-Lunel AM, Varelas X, Wambach JA, Cole FS, Hamvas A, Young LR, Liesa M, Emili A, Guttentag SH, Shirihai OS, Beers MF, Kotton DN. Alysandratos KD, et al. Among authors: kook s. Cell Rep. 2021 Aug 31;36(9):109636. doi: 10.1016/j.celrep.2021.109636. Cell Rep. 2021. PMID: 34469722 Free PMC article.
Alveolar repair following LPS-induced injury requires cell-ECM interactions.
Sucre JM, Bock F, Negretti NM, Benjamin JT, Gulleman PM, Dong X, Ferguson KT, Jetter CS, Han W, Liu Y, Kook S, Gokey JJ, Guttentag SH, Kropski JA, Blackwell TS, Zent R, Plosa EJ. Sucre JM, et al. Among authors: kook s. JCI Insight. 2023 Jul 24;8(14):e167211. doi: 10.1172/jci.insight.167211. JCI Insight. 2023. PMID: 37279065 Free PMC article.
202 results