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mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells.
Bevers S, Kooijmans SAA, Van de Velde E, Evers MJW, Seghers S, Gitz-Francois JJJM, van Kronenburg NCH, Fens MHAM, Mastrobattista E, Hassler L, Sork H, Lehto T, Ahmed KE, El Andaloussi S, Fiedler K, Breckpot K, Maes M, Van Hoorick D, Bastogne T, Schiffelers RM, De Koker S. Bevers S, et al. Among authors: kooijmans saa. Mol Ther. 2022 Sep 7;30(9):3078-3094. doi: 10.1016/j.ymthe.2022.07.007. Epub 2022 Jul 12. Mol Ther. 2022. PMID: 35821637 Free PMC article.
Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety.
Van der Jeught K, De Koker S, Bialkowski L, Heirman C, Tjok Joe P, Perche F, Maenhout S, Bevers S, Broos K, Deswarte K, Malard V, Hammad H, Baril P, Benvegnu T, Jaffrès PA, Kooijmans SAA, Schiffelers R, Lienenklaus S, Midoux P, Pichon C, Breckpot K, Thielemans K. Van der Jeught K, et al. Among authors: kooijmans saa. ACS Nano. 2018 Oct 23;12(10):9815-9829. doi: 10.1021/acsnano.8b00966. Epub 2018 Oct 1. ACS Nano. 2018. PMID: 30256609 Free article.
Exosome mimetics: a novel class of drug delivery systems.
Kooijmans SA, Vader P, van Dommelen SM, van Solinge WW, Schiffelers RM. Kooijmans SA, et al. Int J Nanomedicine. 2012;7:1525-41. doi: 10.2147/IJN.S29661. Epub 2012 Mar 16. Int J Nanomedicine. 2012. PMID: 22619510 Free PMC article. Review.
Tumour-bound RNA-laden exosomes.
Kooijmans SAA, Vader P, Schiffelers RM. Kooijmans SAA, et al. Nat Biomed Eng. 2017 Aug;1(8):634-636. doi: 10.1038/s41551-017-0119-4. Nat Biomed Eng. 2017. PMID: 31015606 No abstract available.
In Situ Gelling Liquid Crystalline System as Local siRNA Delivery System.
Borgheti-Cardoso LN, Kooijmans SAA, Fens MHAM, van der Meel R, Vicentini FTMC, Fantini MCA, Bentley MVLB, Schiffelers RM. Borgheti-Cardoso LN, et al. Among authors: kooijmans saa. Mol Pharm. 2017 May 1;14(5):1681-1690. doi: 10.1021/acs.molpharmaceut.6b01141. Epub 2017 Mar 28. Mol Pharm. 2017. PMID: 28291360
25 results