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Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity.
Grajchen E, Loix M, Baeten P, Côrte-Real BF, Hamad I, Vanherle S, Haidar M, Dehairs J, Broos JY, Ntambi JM, Zimmermann R, Breinbauer R, Stinissen P, Hellings N, Verberk SGS, Kooij G, Giera M, Swinnen JV, Broux B, Kleinewietfeld M, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: kooij g. Cell Mol Immunol. 2023 Jun;20(6):666-679. doi: 10.1038/s41423-023-01011-2. Epub 2023 Apr 12. Cell Mol Immunol. 2023. PMID: 37041314 Free PMC article.
Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids.
Fiala M, Kooij G, Wagner K, Hammock B, Pellegrini M. Fiala M, et al. Among authors: kooij g. FASEB J. 2017 Aug;31(8):3229-3239. doi: 10.1096/fj.201700065R. Epub 2017 Apr 18. FASEB J. 2017. PMID: 28420693 Free PMC article. Review.
Therefore, accumulating preclinical and preliminary clinical evidence indicates that omega-3 supplementation should be tested in a randomized controlled clinical trial and that the analysis should involve the apolipoprotein E genotype and intervening conditions during trial.-Fial …
Therefore, accumulating preclinical and preliminary clinical evidence indicates that omega-3 supplementation should be tested in a randomize …
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques.
Baardman J, Verberk SGS, van der Velden S, Gijbels MJJ, van Roomen CPPA, Sluimer JC, Broos JY, Griffith GR, Prange KHM, van Weeghel M, Lakbir S, Molenaar D, Meinster E, Neele AE, Kooij G, de Vries HE, Lutgens E, Wellen KE, de Winther MPJ, Van den Bossche J. Baardman J, et al. Among authors: kooij g. Nat Commun. 2020 Dec 8;11(1):6296. doi: 10.1038/s41467-020-20141-z. Nat Commun. 2020. PMID: 33293558 Free PMC article.
Pro-resolving lipid mediator lipoxin A4 attenuates neuro-inflammation by modulating T cell responses and modifies the spinal cord lipidome.
Derada Troletti C, Enzmann G, Chiurchiù V, Kamermans A, Tietz SM, Norris PC, Jahromi NH, Leuti A, van der Pol SMA, Schouten M, Serhan CN, de Vries HE, Engelhardt B, Kooij G. Derada Troletti C, et al. Among authors: kooij g. Cell Rep. 2021 Jun 1;35(9):109201. doi: 10.1016/j.celrep.2021.109201. Cell Rep. 2021. PMID: 34077725 Free PMC article.
P-glycoprotein acts as an immunomodulator during neuroinflammation.
Kooij G, Backer R, Koning JJ, Reijerkerk A, van Horssen J, van der Pol SM, Drexhage J, Schinkel A, Dijkstra CD, den Haan JM, Geijtenbeek TB, de Vries HE. Kooij G, et al. PLoS One. 2009 Dec 8;4(12):e8212. doi: 10.1371/journal.pone.0008212. PLoS One. 2009. PMID: 19997559 Free PMC article.
64 results