Nrf2-lncRNA controls cell fate by modulating p53-dependent Nrf2 activation as an miRNA sponge for Plk2 and p21cip1.
Joo MS, Shin SB, Kim EJ, Koo JH, Yim H, Kim SG.
Joo MS, et al.
FASEB J. 2019 Jul;33(7):7953-7969. doi: 10.1096/fj.201802744R. Epub 2019 Mar 21.
FASEB J. 2019.
PMID: 30897343
Collectively, Nrf2-lncRNA promotes Plk2 and p21(cip1) translation by competing for specific miRNAs and activating Nrf2 under surviving conditions from oxidative stress, implying that Nrf2-lncRNA serves as a fine-tuning rheostat for cell fate decision.-Joo, M. S., Shin, S.-B., Kim …
Collectively, Nrf2-lncRNA promotes Plk2 and p21(cip1) translation by competing for specific miRNAs and activating Nrf2 under surviving condi …