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HDL-Targeting Therapeutics: Past, Present and Future.
Zakiev E, Feng M, Sukhorukov V, Kontush A. Zakiev E, et al. Among authors: kontush a. Curr Pharm Des. 2017;23(8):1207-1215. doi: 10.2174/1381612822666161027153140. Curr Pharm Des. 2017. PMID: 27799042 Review.
Poor glycemic control in type 2 diabetes enhances functional and compositional alterations of small, dense HDL3c.
Gomez Rosso L, Lhomme M, Meroño T, Dellepiane A, Sorroche P, Hedjazi L, Zakiev E, Sukhorukov V, Orekhov A, Gasparri J, Chapman MJ, Brites F, Kontush A. Gomez Rosso L, et al. Among authors: kontush a. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Feb;1862(2):188-195. doi: 10.1016/j.bbalip.2016.10.014. Epub 2016 Nov 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 27815221
HDL activates expression of genes stimulating cholesterol efflux in human monocyte-derived macrophages.
Orekhov AN, Pushkarsky T, Oishi Y, Nikiforov NG, Zhelankin AV, Dubrovsky L, Makeev VJ, Foxx K, Jin X, Kruth HS, Sobenin IA, Sukhorukov VN, Zakiev ER, Kontush A, Le Goff W, Bukrinsky M. Orekhov AN, et al. Among authors: kontush a. Exp Mol Pathol. 2018 Oct;105(2):202-207. doi: 10.1016/j.yexmp.2018.08.003. Epub 2018 Aug 16. Exp Mol Pathol. 2018. PMID: 30118702 Free PMC article.
Glycosylation of human plasma lipoproteins reveals a high level of diversity, which directly impacts their functional properties.
Sukhorukov V, Gudelj I, Pučić-Baković M, Zakiev E, Orekhov A, Kontush A, Lauc G. Sukhorukov V, et al. Among authors: kontush a. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):643-653. doi: 10.1016/j.bbalip.2019.01.005. Epub 2019 Jan 12. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30641224 Free article.
Free cholesterol transfer to high-density lipoprotein (HDL) upon triglyceride lipolysis underlies the U-shape relationship between HDL-cholesterol and cardiovascular disease.
Feng M, Darabi M, Tubeuf E, Canicio A, Lhomme M, Frisdal E, Lanfranchi-Lebreton S, Matheron L, Rached F, Ponnaiah M, Serrano CV Jr, Santos RD, Brites F, Bolbach G, Gautier E, Huby T, Carrie A, Bruckert E, Guerin M, Couvert P, Giral P, Lesnik P, Le Goff W, Guillas I, Kontush A. Feng M, et al. Among authors: kontush a. Eur J Prev Cardiol. 2020 Oct;27(15):1606-1616. doi: 10.1177/2047487319894114. Epub 2019 Dec 15. Eur J Prev Cardiol. 2020. PMID: 31840535 Free article.
HDL-targeted therapies: progress, failures and future.
Kingwell BA, Chapman MJ, Kontush A, Miller NE. Kingwell BA, et al. Among authors: kontush a. Nat Rev Drug Discov. 2014 Jun;13(6):445-64. doi: 10.1038/nrd4279. Epub 2014 May 23. Nat Rev Drug Discov. 2014. PMID: 24854407 Review.
HDL-Targeted Therapies During Myocardial Infarction.
Sposito AC, Carmo HR, Barreto J, Sun L, Carvalho LSF, Feinstein SB, Zanotti I, Kontush A, Remaley A. Sposito AC, et al. Among authors: kontush a. Cardiovasc Drugs Ther. 2019 Jun;33(3):371-381. doi: 10.1007/s10557-019-06865-1. Cardiovasc Drugs Ther. 2019. PMID: 30778806 Review.
166 results