Konstantopoulos D - Search Results

1

Single-cell multimodal analysis identifies common regulatory programs in synovial fibroblasts of rheumatoid arthritis patients and modeled TNF-driven arthritis.

Armaka M, Konstantopoulos D, Tzaferis C, Lavigne MD, Sakkou M, Liakos A, Sfikakis PP, Dimopoulos MA, Fousteri M, Kollias G. Armaka M, et al. Among authors: konstantopoulos d. Genome Med. 2022 Jul 26;14(1):78. doi: 10.1186/s13073-022-01081-3. Genome Med. 2022. PMID: 35879783 Free PMC article.

2

Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate.

Lavigne MD, Konstantopoulos D, Ntakou-Zamplara KZ, Liakos A, Fousteri M. Lavigne MD, et al. Among authors: konstantopoulos d. Nat Commun. 2017 Dec 12;8(1):2076. doi: 10.1038/s41467-017-02145-4. Nat Commun. 2017. PMID: 29233992 Free PMC article.

3

Continuous transcription initiation guarantees robust repair of all transcribed genes and regulatory regions.

Liakos A, Konstantopoulos D, Lavigne MD, Fousteri M. Liakos A, et al. Among authors: konstantopoulos d. Nat Commun. 2020 Feb 14;11(1):916. doi: 10.1038/s41467-020-14566-9. Nat Commun. 2020. PMID: 32060325 Free PMC article.

4

MAP3K8 Regulates Cox-2-Mediated Prostaglandin E₂ Production in the Lung and Suppresses Pulmonary Inflammation and Fibrosis.

Zannikou M, Barbayianni I, Fanidis D, Grigorakaki T, Vlachopoulou E, Konstantopoulos D, Fousteri M, Nikitopoulou I, Kotanidou A, Kaffe E, Aidinis V. Zannikou M, et al. Among authors: konstantopoulos d. J Immunol. 2021 Feb 1;206(3):607-620. doi: 10.4049/jimmunol.2000862. Epub 2020 Dec 18. J Immunol. 2021. PMID: 33443087

5

aniFOUND: analysing the associated proteome and genomic landscape of the repaired nascent non-replicative chromatin.

Stefos GC, Szantai E, Konstantopoulos D, Samiotaki M, Fousteri M. Stefos GC, et al. Among authors: konstantopoulos d. Nucleic Acids Res. 2021 Jun 21;49(11):e64. doi: 10.1093/nar/gkab144. Nucleic Acids Res. 2021. PMID: 33693861 Free PMC article.

6

Histone H2Bub dynamics in the 5' region of active genes are tightly linked to the UV-induced transcriptional response.

Fanourgakis S, Synacheri AC, Lavigne MD, Konstantopoulos D, Fousteri M. Fanourgakis S, et al. Among authors: konstantopoulos d. Comput Struct Biotechnol J. 2022 Dec 13;21:614-629. doi: 10.1016/j.csbj.2022.12.013. eCollection 2023. Comput Struct Biotechnol J. 2022. PMID: 36659919 Free PMC article.

7

Enhanced frequency of transcription pre-initiation complexes assembly after exposure to UV irradiation results in increased repair activity and reduced probabilities for mutagenesis.

Liakos A, Synacheri AC, Konstantopoulos D, Stefos GC, Lavigne MD, Fousteri M. Liakos A, et al. Among authors: konstantopoulos d. Nucleic Acids Res. 2023 Sep 8;51(16):8575-8586. doi: 10.1093/nar/gkad593. Nucleic Acids Res. 2023. PMID: 37470822 Free PMC article.

8

SCALA: A complete solution for multimodal analysis of single-cell Next Generation Sequencing data.

Tzaferis C, Karatzas E, Baltoumas FA, Pavlopoulos GA, Kollias G, Konstantopoulos D. Tzaferis C, et al. Among authors: konstantopoulos d. Comput Struct Biotechnol J. 2023 Oct 20;21:5382-5393. doi: 10.1016/j.csbj.2023.10.032. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 38022693 Free PMC article.

9

Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer.

Simigdala N, Chalari A, Sklirou AD, Chavdoula E, Papafotiou G, Melissa P, Kafalidou A, Paschalidis N, Pateras IS, Athanasiadis E, Konstantopoulos D, Trougakos IP, Klinakis A. Simigdala N, et al. Among authors: konstantopoulos d. Cell Mol Life Sci. 2023 Mar 18;80(4):100. doi: 10.1007/s00018-023-04734-7. Cell Mol Life Sci. 2023. PMID: 36933062 Free PMC article.

10

Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways.

Morianos I, Trochoutsou AI, Papadopoulou G, Semitekolou M, Banos A, Konstantopoulos D, Manousopoulou A, Kapasa M, Wei P, Lomenick B, Belaidi E, Kalamatas T, Karageorgiou K, Doskas T, Sallusto F, Pan F, Garbis SD, Quintana FJ, Xanthou G. Morianos I, et al. Among authors: konstantopoulos d. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12269-12280. doi: 10.1073/pnas.1918196117. Epub 2020 May 14. Proc Natl Acad Sci U S A. 2020. PMID: 32409602 Free PMC article.

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