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Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology.
Gnoth K, Piechotta A, Kleinschmidt M, Konrath S, Schenk M, Taudte N, Ramsbeck D, Rieckmann V, Geissler S, Eichentopf R, Barendrecht S, Hartlage-Rübsamen M, Demuth HU, Roßner S, Cynis H, Rahfeld JU, Schilling S. Gnoth K, et al. Among authors: konrath s. Alzheimers Res Ther. 2020 Nov 14;12(1):149. doi: 10.1186/s13195-020-00719-x. Alzheimers Res Ther. 2020. PMID: 33189132 Free PMC article.
NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis.
Vara D, Mailer RK, Tarafdar A, Wolska N, Heestermans M, Konrath S, Spaeth M, Renné T, Schröder K, Pula G. Vara D, et al. Among authors: konrath s. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):683-697. doi: 10.1161/ATVBAHA.120.315565. Epub 2020 Dec 3. Arterioscler Thromb Vasc Biol. 2021. PMID: 33267663 Free PMC article.
Liver damage promotes pro-inflammatory T-cell responses against apolipoprotein B-100.
Plochg BFJ, Englert H, Rangaswamy C, Konrath S, Malle M, Lampalzer S, Beisel C, Wollin S, Frye M, Aberle J, Kluwe J, Renné T, Mailer RK. Plochg BFJ, et al. Among authors: konrath s. J Intern Med. 2022 May;291(5):648-664. doi: 10.1111/joim.13434. Epub 2022 Jan 13. J Intern Med. 2022. PMID: 34914849 Free article.
Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation.
Englert H, Rangaswamy C, Deppermann C, Sperhake JP, Krisp C, Schreier D, Gordon E, Konrath S, Haddad M, Pula G, Mailer RK, Schlüter H, Kluge S, Langer F, Püschel K, Panousis K, Stavrou EX, Maas C, Renné T, Frye M. Englert H, et al. Among authors: konrath s. EBioMedicine. 2021 May;67:103382. doi: 10.1016/j.ebiom.2021.103382. Epub 2021 May 14. EBioMedicine. 2021. PMID: 34000623 Free PMC article.
The contact system in liver injury.
Rangaswamy C, Mailer RK, Englert H, Konrath S, Renné T. Rangaswamy C, et al. Among authors: konrath s. Semin Immunopathol. 2021 Aug;43(4):507-517. doi: 10.1007/s00281-021-00876-7. Epub 2021 Jun 14. Semin Immunopathol. 2021. PMID: 34125270 Free PMC article. Review.
Identification of the factor XII contact activation site enables sensitive coagulation diagnostics.
Heestermans M, Naudin C, Mailer RK, Konrath S, Klaetschke K, Jämsä A, Frye M, Deppermann C, Pula G, Kuta P, Friese MA, Gelderblom M, Sickmann A, Preston RJS, Nofer JR, Rose-John S, Butler LM, Salomon O, Stavrou EX, Renné T. Heestermans M, et al. Among authors: konrath s. Nat Commun. 2021 Sep 22;12(1):5596. doi: 10.1038/s41467-021-25888-7. Nat Commun. 2021. PMID: 34552086 Free PMC article.
An update on factor XII-driven vascular inflammation.
Mailer RK, Rangaswamy C, Konrath S, Emsley J, Renné T. Mailer RK, et al. Among authors: konrath s. Biochim Biophys Acta Mol Cell Res. 2022 Jan;1869(1):119166. doi: 10.1016/j.bbamcr.2021.119166. Epub 2021 Oct 24. Biochim Biophys Acta Mol Cell Res. 2022. PMID: 34699874 Free article. Review.
Targeting NETs using dual-active DNase1 variants.
Englert H, Göbel J, Khong D, Omidi M, Wolska N, Konrath S, Frye M, Mailer RK, Beerens M, Gerwers JC, Preston RJS, Odeberg J, Butler LM, Maas C, Stavrou EX, Fuchs TA, Renné T. Englert H, et al. Among authors: konrath s. Front Immunol. 2023 May 23;14:1181761. doi: 10.3389/fimmu.2023.1181761. eCollection 2023. Front Immunol. 2023. PMID: 37287977 Free PMC article.
46 results