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Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity.
Jurášek M, Džubák P, Rimpelová S, Sedlák D, Konečný P, Frydrych I, Gurská S, Hajdúch M, Bogdanová K, Kolář M, Müller T, Kmoníčková E, Ruml T, Harmatha J, Drašar PB. Jurášek M, et al. Among authors: konecny p. Steroids. 2017 Jan;117:97-104. doi: 10.1016/j.steroids.2016.08.011. Epub 2016 Aug 17. Steroids. 2017. PMID: 27543674
Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.
Bourderioux A, Naus P, Perlíková P, Pohl R, Pichová I, Votruba I, Dzubák P, Konecný P, Hajdúch M, Stray KM, Wang T, Ray AS, Feng JY, Birkus G, Cihlar T, Hocek M. Bourderioux A, et al. Among authors: konecny p. J Med Chem. 2011 Aug 11;54(15):5498-507. doi: 10.1021/jm2005173. Epub 2011 Jul 11. J Med Chem. 2011. PMID: 21711054
Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia.
Spenerova M, Dzubak P, Srovnal J, Radova L, Burianova R, Konecny P, Salkova S, Novak Z, Pospisilova D, Stary J, Blazek B, Hak J, Votava T, Timr P, Kaiserova E, Bubanska E, Mihal V, Hajduch M. Spenerova M, et al. Among authors: konecny p. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014 Sep;158(3):422-7. doi: 10.5507/bp.2012.059. Epub 2012 Oct 31. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014. PMID: 23128824 Free article.
Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.
Snášel J, Nauš P, Dostál J, Hnízda A, Fanfrlík J, Brynda J, Bourderioux A, Dušek M, Dvořáková H, Stolaříková J, Zábranská H, Pohl R, Konečný P, Džubák P, Votruba I, Hajdúch M, Rezáčová P, Veverka V, Hocek M, Pichová I. Snášel J, et al. Among authors: konecny p. J Med Chem. 2014 Oct 23;57(20):8268-79. doi: 10.1021/jm500497v. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25259627
Pathophysiologically relevant in vitro tumor models for drug screening.
Das V, Bruzzese F, Konečný P, Iannelli F, Budillon A, Hajdúch M. Das V, et al. Among authors: konecny p. Drug Discov Today. 2015 Jul;20(7):848-55. doi: 10.1016/j.drudis.2015.04.004. Epub 2015 Apr 20. Drug Discov Today. 2015. PMID: 25908576 Review.
149 results