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Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-β-IGFBP7 axis.
Ko T, Nomura S, Yamada S, Fujita K, Fujita T, Satoh M, Oka C, Katoh M, Ito M, Katagiri M, Sassa T, Zhang B, Hatsuse S, Yamada T, Harada M, Toko H, Amiya E, Hatano M, Kinoshita O, Nawata K, Abe H, Ushiku T, Ono M, Ikeuchi M, Morita H, Aburatani H, Komuro I. Ko T, et al. Among authors: komuro i. Nat Commun. 2022 Jun 7;13(1):3275. doi: 10.1038/s41467-022-30630-y. Nat Commun. 2022. PMID: 35672400 Free PMC article.
Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4.
Monzen K, Shiojima I, Hiroi Y, Kudoh S, Oka T, Takimoto E, Hayashi D, Hosoda T, Habara-Ohkubo A, Nakaoka T, Fujita T, Yazaki Y, Komuro I. Monzen K, et al. Among authors: komuro i. Mol Cell Biol. 1999 Oct;19(10):7096-105. doi: 10.1128/MCB.19.10.7096. Mol Cell Biol. 1999. PMID: 10490646 Free PMC article.
Up-regulation of natriuretic peptides in the ventricle of Csx/Nkx2-5 transgenic mice.
Takimoto E, Mizuno T, Terasaki F, Shimoyama M, Honda H, Shiojima I, Hiroi Y, Oka T, Hayashi D, Hirai H, Kudoh S, Toko H, Kawamura K, Nagai R, Yazaki Y, Komuro I. Takimoto E, et al. Among authors: komuro i. Biochem Biophys Res Commun. 2000 Apr 21;270(3):1074-9. doi: 10.1006/bbrc.2000.2561. Biochem Biophys Res Commun. 2000. PMID: 10772952
gp130 plays a critical role in pressure overload-induced cardiac hypertrophy.
Uozumi H, Hiroi Y, Zou Y, Takimoto E, Toko H, Niu P, Shimoyama M, Yazaki Y, Nagai R, Komuro I. Uozumi H, et al. Among authors: komuro i. J Biol Chem. 2001 Jun 22;276(25):23115-9. doi: 10.1074/jbc.M100814200. Epub 2001 Mar 21. J Biol Chem. 2001. PMID: 11262406 Free article.
1,436 results