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Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.
Shioyama W, Nakaoka Y, Higuchi K, Minami T, Taniyama Y, Nishida K, Kidoya H, Sonobe T, Naito H, Arita Y, Hashimoto T, Kuroda T, Fujio Y, Shirai M, Takakura N, Morishita R, Yamauchi-Takihara K, Kodama T, Hirano T, Mochizuki N, Komuro I. Shioyama W, et al. Among authors: komuro i. Circ Res. 2011 Mar 18;108(6):664-75. doi: 10.1161/CIRCRESAHA.110.232223. Epub 2011 Feb 3. Circ Res. 2011. PMID: 21293003
Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice.
Higuchi K, Nakaoka Y, Shioyama W, Arita Y, Hashimoto T, Yasui T, Ikeoka K, Kuroda T, Minami T, Nishida K, Fujio Y, Yamauchi-Takihara K, Shirai M, Mochizuki N, Komuro I. Higuchi K, et al. Among authors: komuro i. Circ J. 2012;76(8):2031-40. doi: 10.1253/circj.cj-11-1507. Epub 2012 May 19. Circ J. 2012. PMID: 22664868 Free article.
Tocilizumab for the treatment of patients with refractory Takayasu arteritis.
Nakaoka Y, Higuchi K, Arita Y, Otsuki M, Yamamoto K, Hashimoto-Kataoka T, Yasui T, Ikeoka K, Ohtani T, Sakata Y, Shima Y, Kumanogoh A, Yamauchi-Takihara K, Tanaka T, Kishimoto T, Komuro I. Nakaoka Y, et al. Among authors: komuro i. Int Heart J. 2013;54(6):405-11. doi: 10.1536/ihj.54.405. Int Heart J. 2013. PMID: 24309452 Free article.
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Arita Y, Nakaoka Y, Matsunaga T, Kidoya H, Yamamizu K, Arima Y, Kataoka-Hashimoto T, Ikeoka K, Yasui T, Masaki T, Yamamoto K, Higuchi K, Park JS, Shirai M, Nishiyama K, Yamagishi H, Otsu K, Kurihara H, Minami T, Yamauchi-Takihara K, Koh GY, Mochizuki N, Takakura N, Sakata Y, Yamashita JK, Komuro I. Arita Y, et al. Among authors: komuro i. Nat Commun. 2014 Jul 29;5:4552. doi: 10.1038/ncomms5552. Nat Commun. 2014. PMID: 25072663 Free PMC article.
Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension.
Hashimoto-Kataoka T, Hosen N, Sonobe T, Arita Y, Yasui T, Masaki T, Minami M, Inagaki T, Miyagawa S, Sawa Y, Murakami M, Kumanogoh A, Yamauchi-Takihara K, Okumura M, Kishimoto T, Komuro I, Shirai M, Sakata Y, Nakaoka Y. Hashimoto-Kataoka T, et al. Among authors: komuro i. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2677-86. doi: 10.1073/pnas.1424774112. Epub 2015 May 4. Proc Natl Acad Sci U S A. 2015. PMID: 25941359 Free PMC article.
1,436 results