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Bone morphogenic protein (BMP) signaling up-regulates neutral sphingomyelinase 2 to suppress chondrocyte maturation via the Akt protein signaling pathway as a negative feedback mechanism.
Kakoi H, Maeda S, Shinohara N, Matsuyama K, Imamura K, Kawamura I, Nagano S, Setoguchi T, Yokouchi M, Ishidou Y, Komiya S. Kakoi H, et al. Among authors: komiya s. J Biol Chem. 2014 Mar 21;289(12):8135-50. doi: 10.1074/jbc.M113.509331. Epub 2014 Feb 6. J Biol Chem. 2014. PMID: 24505141 Free PMC article.
Role of GLI2 in the growth of human osteosarcoma.
Nagao H, Ijiri K, Hirotsu M, Ishidou Y, Yamamoto T, Nagano S, Takizawa T, Nakashima K, Komiya S, Setoguchi T. Nagao H, et al. Among authors: komiya s. J Pathol. 2011 Jun;224(2):169-79. doi: 10.1002/path.2880. Epub 2011 Apr 19. J Pathol. 2011. PMID: 21506130
RBPJ is a novel target for rhabdomyosarcoma therapy.
Nagao H, Setoguchi T, Kitamoto S, Ishidou Y, Nagano S, Yokouchi M, Abematsu M, Kawabata N, Maeda S, Yonezawa S, Komiya S. Nagao H, et al. Among authors: komiya s. PLoS One. 2012;7(7):e39268. doi: 10.1371/journal.pone.0039268. Epub 2012 Jul 9. PLoS One. 2012. PMID: 22792167 Free PMC article.
356 results