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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M. Komatsu M, et al. Among authors: kominami e. Nat Cell Biol. 2010 Mar;12(3):213-23. doi: 10.1038/ncb2021. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173742
LC3 conjugation system in mammalian autophagy.
Tanida I, Ueno T, Kominami E. Tanida I, et al. Among authors: kominami e. Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18. doi: 10.1016/j.biocel.2004.05.009. Int J Biochem Cell Biol. 2004. PMID: 15325588 Free PMC article. Review.
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T. Komatsu M, et al. Among authors: kominami e. J Cell Biol. 2005 May 9;169(3):425-34. doi: 10.1083/jcb.200412022. Epub 2005 May 2. J Cell Biol. 2005. PMID: 15866887 Free PMC article.
Autophagy and neurodegeneration.
Komatsu M, Kominami E, Tanaka K. Komatsu M, et al. Among authors: kominami e. Autophagy. 2006 Oct-Dec;2(4):315-7. doi: 10.4161/auto.2974. Epub 2006 Oct 2. Autophagy. 2006. PMID: 16874063
Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K. Komatsu M, et al. Among authors: kominami e. Cell. 2007 Dec 14;131(6):1149-63. doi: 10.1016/j.cell.2007.10.035. Cell. 2007. PMID: 18083104 Free article.
Structural basis for sorting mechanism of p62 in selective autophagy.
Ichimura Y, Kumanomidou T, Sou YS, Mizushima T, Ezaki J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M. Ichimura Y, et al. Among authors: kominami e. J Biol Chem. 2008 Aug 15;283(33):22847-57. doi: 10.1074/jbc.M802182200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524774 Free article.
Selective turnover of p62/A170/SQSTM1 by autophagy.
Ichimura Y, Kominami E, Tanaka K, Komatsu M. Ichimura Y, et al. Among authors: kominami e. Autophagy. 2008 Nov;4(8):1063-6. doi: 10.4161/auto.6826. Epub 2008 Nov 20. Autophagy. 2008. PMID: 18776737
324 results