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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition.
Lipinski B, Unmuth L, Arras P, Becker S, Bauer C, Toleikis L, Krah S, Doerner A, Yanakieva D, Boje AS, Klausz K, Peipp M, Siegmund V, Evers A, Kolmar H, Pekar L, Zielonka S. Lipinski B, et al. Among authors: kolmar h. MAbs. 2023 Jan-Dec;15(1):2236265. doi: 10.1080/19420862.2023.2236265. MAbs. 2023. PMID: 37469014 Free PMC article.
Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format.
Yanakieva D, Vollmer L, Evers A, Siegmund V, Arras P, Pekar L, Doerner A, Valldorf B, Kolmar H, Zielonka S, Krah S. Yanakieva D, et al. Among authors: kolmar h. Front Immunol. 2023 Oct 24;14:1238313. doi: 10.3389/fimmu.2023.1238313. eCollection 2023. Front Immunol. 2023. PMID: 37942319 Free PMC article.
225 results