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Short interruptions of TNF-inhibitor treatment can be associated with treatment failure in patients with immune-mediated diseases.
Lamberg T, Sipponen T, Valtanen S, Eklund KK, Mälkönen T, Aalto K, Mikola K, Kolho KL, Leinonen S, Isomäki P, Mäkinen H, Vidqvist KL, Kokko A, Huilaja L, Kyllönen M, Keskitalo P, Sard S, Vähäsalo P, Koskela R, Kröger L, Lahtinen P, Haapala AM, Korkatti K, Sokka-Isler T, Jokiranta TS; BLING Research Group. Lamberg T, et al. Among authors: kolho kl. Autoimmunity. 2022 Aug;55(5):275-284. doi: 10.1080/08916934.2022.2067985. Epub 2022 Apr 28. Autoimmunity. 2022. PMID: 35481450
IL-23/IL-17 immunity as a hallmark of Crohn's disease.
Hölttä V, Klemetti P, Sipponen T, Westerholm-Ormio M, Kociubinski G, Salo H, Räsänen L, Kolho KL, Färkkilä M, Savilahti E, Vaarala O. Hölttä V, et al. Among authors: kolho kl. Inflamm Bowel Dis. 2008 Sep;14(9):1175-84. doi: 10.1002/ibd.20475. Inflamm Bowel Dis. 2008. PMID: 18512248
Changes in matrix metalloproteinase (MMP) and tissue inhibitors of metalloproteinases (TIMP) expression profile in Crohn's disease after immunosuppressive treatment correlate with histological score and calprotectin values.
Mäkitalo L, Sipponen T, Kärkkäinen P, Kolho KL, Saarialho-Kere U. Mäkitalo L, et al. Among authors: kolho kl. Int J Colorectal Dis. 2009 Oct;24(10):1157-67. doi: 10.1007/s00384-009-0756-5. Epub 2009 Aug 4. Int J Colorectal Dis. 2009. PMID: 19652986
274 results