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Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, Glawitsch L, Heitzer E, Schulz TJ, Schupp M, Sun W, Dong H, Ghosh A, Hoffmann A, Kratky D, Hinte LC, von Meyenn F, Heck AJR, Blüher M, Herzig S, Wolfrum C, Prokesch A. Reinisch I, et al. Among authors: kolb d. Nat Commun. 2024 Feb 15;15(1):1391. doi: 10.1038/s41467-024-45724-y. Nat Commun. 2024. PMID: 38360943 Free PMC article.
Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
Chandak PG, Radovic B, Aflaki E, Kolb D, Buchebner M, Fröhlich E, Magnes C, Sinner F, Haemmerle G, Zechner R, Tabas I, Levak-Frank S, Kratky D. Chandak PG, et al. Among authors: kolb d. J Biol Chem. 2010 Jun 25;285(26):20192-201. doi: 10.1074/jbc.M110.107854. Epub 2010 Apr 27. J Biol Chem. 2010. PMID: 20424161 Free PMC article.
C16 ceramide is crucial for triacylglycerol-induced apoptosis in macrophages.
Aflaki E, Doddapattar P, Radović B, Povoden S, Kolb D, Vujić N, Wegscheider M, Koefeler H, Hornemann T, Graier WF, Malli R, Madeo F, Kratky D. Aflaki E, et al. Among authors: kolb d. Cell Death Dis. 2012 Mar 15;3(3):e280. doi: 10.1038/cddis.2012.17. Cell Death Dis. 2012. PMID: 22419109 Free PMC article.
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice.
Doddapattar P, Radović B, Patankar JV, Obrowsky S, Jandl K, Nusshold C, Kolb D, Vujić N, Doshi L, Chandak PG, Goeritzer M, Ahammer H, Hoefler G, Sattler W, Kratky D. Doddapattar P, et al. Among authors: kolb d. Mol Nutr Food Res. 2013 Oct;57(10):1718-28. doi: 10.1002/mnfr.201200794. Epub 2013 May 3. Mol Nutr Food Res. 2013. PMID: 23650230 Free PMC article.
NAT8L (N-acetyltransferase 8-like) accelerates lipid turnover and increases energy expenditure in brown adipocytes.
Pessentheiner AR, Pelzmann HJ, Walenta E, Schweiger M, Groschner LN, Graier WF, Kolb D, Uno K, Miyazaki T, Nitta A, Rieder D, Prokesch A, Bogner-Strauss JG. Pessentheiner AR, et al. Among authors: kolb d. J Biol Chem. 2013 Dec 13;288(50):36040-51. doi: 10.1074/jbc.M113.491324. Epub 2013 Oct 23. J Biol Chem. 2013. PMID: 24155240 Free PMC article.
Deletion of CGI-58 or adipose triglyceride lipase differently affects macrophage function and atherosclerosis.
Goeritzer M, Schlager S, Radovic B, Madreiter CT, Rainer S, Thomas G, Lord CC, Sacks J, Brown AL, Vujic N, Obrowsky S, Sachdev V, Kolb D, Chandak PG, Graier WF, Sattler W, Brown JM, Kratky D. Goeritzer M, et al. Among authors: kolb d. J Lipid Res. 2014 Dec;55(12):2562-75. doi: 10.1194/jlr.M052613. Epub 2014 Oct 14. J Lipid Res. 2014. PMID: 25316883 Free PMC article.
Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.
Schlager S, Goeritzer M, Jandl K, Frei R, Vujic N, Kolb D, Strohmaier H, Dorow J, Eichmann TO, Rosenberger A, Wölfler A, Lass A, Kershaw EE, Ceglarek U, Dichlberger A, Heinemann A, Kratky D. Schlager S, et al. Among authors: kolb d. J Leukoc Biol. 2015 Nov;98(5):837-50. doi: 10.1189/jlb.3A0515-206R. Epub 2015 Jun 24. J Leukoc Biol. 2015. PMID: 26109679 Free PMC article.
Active autophagy but not lipophagy in macrophages with defective lipolysis.
Goeritzer M, Vujic N, Schlager S, Chandak PG, Korbelius M, Gottschalk B, Leopold C, Obrowsky S, Rainer S, Doddapattar P, Aflaki E, Wegscheider M, Sachdev V, Graier WF, Kolb D, Radovic B, Kratky D. Goeritzer M, et al. Among authors: kolb d. Biochim Biophys Acta. 2015 Oct;1851(10):1304-1316. doi: 10.1016/j.bbalip.2015.06.005. Epub 2015 Jul 2. Biochim Biophys Acta. 2015. PMID: 26143381 Free PMC article.
N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes.
Prokesch A, Pelzmann HJ, Pessentheiner AR, Huber K, Madreiter-Sokolowski CT, Drougard A, Schittmayer M, Kolb D, Magnes C, Trausinger G, Graier WF, Birner-Gruenberger R, Pospisilik JA, Bogner-Strauss JG. Prokesch A, et al. Among authors: kolb d. Sci Rep. 2016 Apr 5;6:23723. doi: 10.1038/srep23723. Sci Rep. 2016. PMID: 27045997 Free PMC article.
200 results