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A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor.
Fukuda T, Kanomata K, Nojima J, Kokabu S, Akita M, Ikebuchi K, Jimi E, Komori T, Maruki Y, Matsuoka M, Miyazono K, Nakayama K, Nanba A, Tomoda H, Okazaki Y, Ohtake A, Oda H, Owan I, Yoda T, Haga N, Furuya H, Katagiri T. Fukuda T, et al. Among authors: kokabu s. Biochem Biophys Res Commun. 2008 Dec 19;377(3):905-9. doi: 10.1016/j.bbrc.2008.10.093. Epub 2008 Oct 24. Biochem Biophys Res Commun. 2008. PMID: 18952055
The role of BMP2 signaling in the skeleton.
Lowery JW, Pazin D, Intini G, Kokabu S, Chappuis V, Capelo LP, Rosen V. Lowery JW, et al. Among authors: kokabu s. Crit Rev Eukaryot Gene Expr. 2011;21(2):177-85. doi: 10.1615/critreveukargeneexpr.v21.i2.60. Crit Rev Eukaryot Gene Expr. 2011. PMID: 22077155
Identification of a novel bone morphogenetic protein (BMP)-inducible transcript, BMP-inducible transcript-1, by utilizing the conserved BMP-responsive elements in the Id genes.
Shin M, Ohte S, Fukuda T, Sasanuma H, Yoneyama K, Kokabu S, Miyamoto A, Tsukamoto S, Hohjoh H, Jimi E, Katagiri T. Shin M, et al. Among authors: kokabu s. J Bone Miner Metab. 2013 Jan;31(1):34-43. doi: 10.1007/s00774-012-0381-1. Epub 2012 Sep 14. J Bone Miner Metab. 2013. PMID: 22976053
Inhibition of BMP2-induced bone formation by the p65 subunit of NF-κB via an interaction with Smad4.
Hirata-Tsuchiya S, Fukushima H, Katagiri T, Ohte S, Shin M, Nagano K, Aoki K, Morotomi T, Sugiyama G, Nakatomi C, Kokabu S, Doi T, Takeuchi H, Ohya K, Terashita M, Hirata M, Kitamura C, Jimi E. Hirata-Tsuchiya S, et al. Among authors: kokabu s. Mol Endocrinol. 2014 Sep;28(9):1460-70. doi: 10.1210/me.2014-1094. Epub 2014 Jul 16. Mol Endocrinol. 2014. PMID: 25029242 Free PMC article.
84 results