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Low Environmental Temperature Exacerbates Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Golden Syrian Hamsters.
Chan JFW, Poon VKM, Chan CCS, Chik KKH, Tsang JOL, Zou Z, Chan CCY, Lee ACY, Li C, Liang R, Cao J, Tang K, Yuen TTT, Hu B, Huang X, Chai Y, Shuai H, Luo C, Cai JP, Chan KH, Sridhar S, Yin F, Kok KH, Chu H, Zhang AJ, Yuan S, Yuen KY. Chan JFW, et al. Among authors: kok kh. Clin Infect Dis. 2022 Aug 24;75(1):e1101-e1111. doi: 10.1093/cid/ciab817. Clin Infect Dis. 2022. PMID: 34536277
Differential cell line susceptibility to the emerging Zika virus: implications for disease pathogenesis, non-vector-borne human transmission and animal reservoirs.
Chan JF, Yip CC, Tsang JO, Tee KM, Cai JP, Chik KK, Zhu Z, Chan CC, Choi GK, Sridhar S, Zhang AJ, Lu G, Chiu K, Lo AC, Tsao SW, Kok KH, Jin DY, Chan KH, Yuen KY. Chan JF, et al. Among authors: kok kh. Emerg Microbes Infect. 2016 Aug 24;5(8):e93. doi: 10.1038/emi.2016.99. Emerg Microbes Infect. 2016. PMID: 27553173 Free PMC article.
Zika Virus Infection in Dexamethasone-immunosuppressed Mice Demonstrating Disseminated Infection with Multi-organ Involvement Including Orchitis Effectively Treated by Recombinant Type I Interferons.
Chan JF, Zhang AJ, Chan CC, Yip CC, Mak WW, Zhu H, Poon VK, Tee KM, Zhu Z, Cai JP, Tsang JO, Chik KK, Yin F, Chan KH, Kok KH, Jin DY, Au-Yeung RK, Yuen KY. Chan JF, et al. Among authors: kok kh. EBioMedicine. 2016 Dec;14:112-122. doi: 10.1016/j.ebiom.2016.11.017. Epub 2016 Nov 12. EBioMedicine. 2016. PMID: 27884655 Free PMC article.
Selective Activation of Type II Interferon Signaling by Zika Virus NS5 Protein.
Chaudhary V, Yuen KS, Chan JF, Chan CP, Wang PH, Cai JP, Zhang S, Liang M, Kok KH, Chan CP, Yuen KY, Jin DY. Chaudhary V, et al. Among authors: kok kh. J Virol. 2017 Jun 26;91(14):e00163-17. doi: 10.1128/JVI.00163-17. Print 2017 Jul 15. J Virol. 2017. PMID: 28468880 Free PMC article.
Immunization With a Novel Human Type 5 Adenovirus-Vectored Vaccine Expressing the Premembrane and Envelope Proteins of Zika Virus Provides Consistent and Sterilizing Protection in Multiple Immunocompetent and Immunocompromised Animal Models.
Guo Q, Chan JF, Poon VK, Wu S, Chan CC, Hou L, Yip CC, Ren C, Cai JP, Zhao M, Zhang AJ, Song X, Chan KH, Wang B, Kok KH, Wen Y, Yuen KY, Chen W. Guo Q, et al. Among authors: kok kh. J Infect Dis. 2018 Jul 2;218(3):365-377. doi: 10.1093/infdis/jiy187. J Infect Dis. 2018. PMID: 29617816
Human tryptophanyl-tRNA synthetase is an IFN-γ-inducible entry factor for Enterovirus.
Yeung ML, Jia L, Yip CCY, Chan JFW, Teng JLL, Chan KH, Cai JP, Zhang C, Zhang AJ, Wong WM, Kok KH, Lau SKP, Woo PCY, Lo JYC, Jin DY, Shih SR, Yuen KY. Yeung ML, et al. Among authors: kok kh. J Clin Invest. 2018 Nov 1;128(11):5163-5177. doi: 10.1172/JCI99411. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30153112 Free PMC article.
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target.
Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. Yuan S, et al. Among authors: kok kh. Nat Commun. 2019 Jan 10;10(1):120. doi: 10.1038/s41467-018-08015-x. Nat Commun. 2019. PMID: 30631056 Free PMC article.
92 results