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JunB is essential for IL-23-dependent pathogenicity of Th17 cells.
Hasan Z, Koizumi SI, Sasaki D, Yamada H, Arakaki N, Fujihara Y, Okitsu S, Shirahata H, Ishikawa H. Hasan Z, et al. Among authors: koizumi si. Nat Commun. 2017 May 30;8:15628. doi: 10.1038/ncomms15628. Nat Commun. 2017. PMID: 28555647 Free PMC article.
The CCR4-NOT deadenylase complex safeguards thymic positive selection by down-regulating aberrant pro-apoptotic gene expression.
Ito-Kureha T, Miyao T, Nishijima S, Suzuki T, Koizumi SI, Villar-Briones A, Takahashi A, Akiyama N, Morita M, Naguro I, Ishikawa H, Ichijo H, Akiyama T, Yamamoto T. Ito-Kureha T, et al. Among authors: koizumi si. Nat Commun. 2020 Dec 2;11(1):6169. doi: 10.1038/s41467-020-19975-4. Nat Commun. 2020. PMID: 33268794 Free PMC article.
Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner.
Koizumi S, Masuko K, Wakita D, Tanaka S, Mitamura R, Kato Y, Tabata H, Nakahara M, Kitamura H, Nishimura T. Koizumi S, et al. Cell Immunol. 2012 Mar-Apr;276(1-2):153-61. doi: 10.1016/j.cellimm.2012.05.002. Epub 2012 May 17. Cell Immunol. 2012. PMID: 22677561 Free article.
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