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Integrin α11β1 is a receptor for collagen XIII.
Koivunen J, Tu H, Kemppainen A, Anbazhagan P, Finnilä MA, Saarakkala S, Käpylä J, Lu N, Heikkinen A, Juffer AH, Heino J, Gullberg D, Pihlajaniemi T. Koivunen J, et al. Cell Tissue Res. 2021 Mar;383(3):1135-1153. doi: 10.1007/s00441-020-03300-y. Epub 2020 Dec 11. Cell Tissue Res. 2021. PMID: 33306155 Free PMC article.
Novel α2β1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require receptor preactivation.
Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J. Nissinen L, et al. Among authors: koivunen j. J Biol Chem. 2012 Dec 28;287(53):44694-702. doi: 10.1074/jbc.M111.309450. Epub 2012 Nov 6. J Biol Chem. 2012. PMID: 23132859 Free PMC article.
Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics.
Nkizinkiko Y, Suneel Kumar BVS, Jeankumar VU, Haikarainen T, Koivunen J, Madhuri C, Yogeeswari P, Venkannagari H, Obaji E, Pihlajaniemi T, Sriram D, Lehtiö L. Nkizinkiko Y, et al. Among authors: koivunen j. Bioorg Med Chem. 2015 Aug 1;23(15):4139-4149. doi: 10.1016/j.bmc.2015.06.063. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26183543
Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage.
Venkannagari H, Verheugd P, Koivunen J, Haikarainen T, Obaji E, Ashok Y, Narwal M, Pihlajaniemi T, Lüscher B, Lehtiö L. Venkannagari H, et al. Among authors: koivunen j. Cell Chem Biol. 2016 Oct 20;23(10):1251-1260. doi: 10.1016/j.chembiol.2016.08.012. Epub 2016 Sep 22. Cell Chem Biol. 2016. PMID: 27667561 Free article.
Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.
Nathubhai A, Haikarainen T, Koivunen J, Murthy S, Koumanov F, Lloyd MD, Holman GD, Pihlajaniemi T, Tosh D, Lehtiö L, Threadgill MD. Nathubhai A, et al. Among authors: koivunen j. J Med Chem. 2017 Jan 26;60(2):814-820. doi: 10.1021/acs.jmedchem.6b01574. Epub 2017 Jan 9. J Med Chem. 2017. PMID: 27983846 Free article.
110 results