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Gene therapy using genome-edited iPS cells for targeting malignant glioma.
Tamura R, Miyoshi H, Imaizumi K, Yo M, Kase Y, Sato T, Sato M, Morimoto Y, Sampetrean O, Kohyama J, Shinozaki M, Miyawaki A, Yoshida K, Saya H, Okano H, Toda M. Tamura R, et al. Among authors: kohyama j. Bioeng Transl Med. 2022 Sep 10;8(5):e10406. doi: 10.1002/btm2.10406. eCollection 2023 Sep. Bioeng Transl Med. 2022. PMID: 37693056 Free PMC article.
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies.
Iwanami A, Gini B, Zanca C, Matsutani T, Assuncao A, Nael A, Dang J, Yang H, Zhu S, Kohyama J, Kitabayashi I, Cavenee WK, Cloughesy TF, Furnari FB, Nakamura M, Toyama Y, Okano H, Mischel PS. Iwanami A, et al. Among authors: kohyama j. Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4339-44. doi: 10.1073/pnas.1217602110. Epub 2013 Feb 25. Proc Natl Acad Sci U S A. 2013. PMID: 23440206 Free PMC article. Clinical Trial.
Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury.
Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, Nakamura M, Okano H. Kawabata S, et al. Among authors: kohyama j. Stem Cell Reports. 2016 Jan 12;6(1):1-8. doi: 10.1016/j.stemcr.2015.11.013. Epub 2015 Dec 24. Stem Cell Reports. 2016. PMID: 26724902 Free PMC article.
Safe and efficient method for cryopreservation of human induced pluripotent stem cell-derived neural stem and progenitor cells by a programmed freezer with a magnetic field.
Nishiyama Y, Iwanami A, Kohyama J, Itakura G, Kawabata S, Sugai K, Nishimura S, Kashiwagi R, Yasutake K, Isoda M, Matsumoto M, Nakamura M, Okano H. Nishiyama Y, et al. Among authors: kohyama j. Neurosci Res. 2016 Jun;107:20-9. doi: 10.1016/j.neures.2015.11.011. Epub 2016 Jan 22. Neurosci Res. 2016. PMID: 26804710 Free article.
Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases.
Sugai K, Fukuzawa R, Shofuda T, Fukusumi H, Kawabata S, Nishiyama Y, Higuchi Y, Kawai K, Isoda M, Kanematsu D, Hashimoto-Tamaoki T, Kohyama J, Iwanami A, Suemizu H, Ikeda E, Matsumoto M, Kanemura Y, Nakamura M, Okano H. Sugai K, et al. Among authors: kohyama j. Mol Brain. 2016 Sep 19;9(1):85. doi: 10.1186/s13041-016-0265-8. Mol Brain. 2016. PMID: 27642008 Free PMC article.
Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury.
Okubo T, Iwanami A, Kohyama J, Itakura G, Kawabata S, Nishiyama Y, Sugai K, Ozaki M, Iida T, Matsubayashi K, Matsumoto M, Nakamura M, Okano H. Okubo T, et al. Among authors: kohyama j. Stem Cell Reports. 2016 Oct 11;7(4):649-663. doi: 10.1016/j.stemcr.2016.08.015. Epub 2016 Sep 22. Stem Cell Reports. 2016. PMID: 27666789 Free PMC article.
187 results