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Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cells.
Masterman KA, Haigh OL, Tullett KM, Leal-Rojas IM, Walpole C, Pearson FE, Cebon J, Schmidt C, O'Brien L, Rosendahl N, Daraj G, Caminschi I, Gschweng EH, Hollis RP, Kohn DB, Lahoud MH, Radford KJ. Masterman KA, et al. Among authors: kohn db. J Immunother Cancer. 2020 Jul;8(2):e000691. doi: 10.1136/jitc-2020-000691. J Immunother Cancer. 2020. PMID: 32737142 Free PMC article.
Transient gene expression by nonintegrating lentiviral vectors.
Nightingale SJ, Hollis RP, Pepper KA, Petersen D, Yu XJ, Yang C, Bahner I, Kohn DB. Nightingale SJ, et al. Among authors: kohn db. Mol Ther. 2006 Jun;13(6):1121-32. doi: 10.1016/j.ymthe.2006.01.008. Epub 2006 Mar 23. Mol Ther. 2006. PMID: 16556511 Free article.
CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.
Chhabra A, Yang L, Wang P, Comin-Anduix B, Das R, Chakraborty NG, Ray S, Mehrotra S, Yang H, Hardee CL, Hollis R, Dorsky DI, Koya R, Kohn DB, Ribas A, Economou JS, Baltimore D, Mukherji B. Chhabra A, et al. Among authors: kohn db. J Immunol. 2008 Jul 15;181(2):1063-70. doi: 10.4049/jimmunol.181.2.1063. J Immunol. 2008. PMID: 18606658 Free PMC article.
Lentiviral vectors with amplified beta cell-specific gene expression.
Shaw KL, Pais E, Ge S, Hardee C, Skelton D, Hollis RP, Crooks GM, Kohn DB. Shaw KL, et al. Among authors: kohn db. Gene Ther. 2009 Aug;16(8):998-1008. doi: 10.1038/gt.2009.49. Epub 2009 May 14. Gene Ther. 2009. PMID: 19440227 Free PMC article.
Regulated expansion of human pancreatic beta-cells.
Pais E, Park J, Alexy T, Nikolian V, Ge S, Shaw K, Senadheera S, Hardee CL, Skelton D, Hollis R, Crooks GM, Kohn DB. Pais E, et al. Among authors: kohn db. Mol Ther. 2010 Jul;18(7):1389-96. doi: 10.1038/mt.2010.63. Epub 2010 Apr 13. Mol Ther. 2010. PMID: 20389286 Free PMC article.
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
Vatakis DN, Koya RC, Nixon CC, Wei L, Kim SG, Avancena P, Bristol G, Baltimore D, Kohn DB, Ribas A, Radu CG, Galic Z, Zack JA. Vatakis DN, et al. Among authors: kohn db. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):E1408-16. doi: 10.1073/pnas.1115050108. Epub 2011 Nov 28. Proc Natl Acad Sci U S A. 2011. PMID: 22123951 Free PMC article.
353 results