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Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy.
Shahzad K, Bock F, Dong W, Wang H, Kopf S, Kohli S, Al-Dabet MM, Ranjan S, Wolter J, Wacker C, Biemann R, Stoyanov S, Reymann K, Söderkvist P, Groß O, Schwenger V, Pahernik S, Nawroth PP, Gröne HJ, Madhusudhan T, Isermann B. Shahzad K, et al. Among authors: kohli s. Kidney Int. 2015 Jan;87(1):74-84. doi: 10.1038/ki.2014.271. Epub 2014 Jul 30. Kidney Int. 2015. PMID: 25075770 Free PMC article.
Defective podocyte insulin signalling through p85-XBP1 promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.
Madhusudhan T, Wang H, Dong W, Ghosh S, Bock F, Thangapandi VR, Ranjan S, Wolter J, Kohli S, Shahzad K, Heidel F, Krueger M, Schwenger V, Moeller MJ, Kalinski T, Reiser J, Chavakis T, Isermann B. Madhusudhan T, et al. Among authors: kohli s. Nat Commun. 2015 Mar 10;6:6496. doi: 10.1038/ncomms7496. Nat Commun. 2015. PMID: 25754093 Free PMC article.
Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination.
Dong W, Wang H, Shahzad K, Bock F, Al-Dabet MM, Ranjan S, Wolter J, Kohli S, Hoffmann J, Dhople VM, Zhu C, Lindquist JA, Esmon CT, Gröne E, Gröne HJ, Madhusudhan T, Mertens PR, Schlüter D, Isermann B. Dong W, et al. Among authors: kohli s. J Am Soc Nephrol. 2015 Nov;26(11):2789-99. doi: 10.1681/ASN.2014080846. Epub 2015 May 26. J Am Soc Nephrol. 2015. PMID: 26015455 Free PMC article.
Caspase-1, but Not Caspase-3, Promotes Diabetic Nephropathy.
Shahzad K, Bock F, Al-Dabet MM, Gadi I, Kohli S, Nazir S, Ghosh S, Ranjan S, Wang H, Madhusudhan T, Nawroth PP, Isermann B. Shahzad K, et al. Among authors: kohli s. J Am Soc Nephrol. 2016 Aug;27(8):2270-5. doi: 10.1681/ASN.2015060676. Epub 2016 Feb 1. J Am Soc Nephrol. 2016. PMID: 26832955 Free PMC article.
Maternal extracellular vesicles and platelets promote preeclampsia via inflammasome activation in trophoblasts.
Kohli S, Ranjan S, Hoffmann J, Kashif M, Daniel EA, Al-Dabet MM, Bock F, Nazir S, Huebner H, Mertens PR, Fischer KD, Zenclussen AC, Offermanns S, Aharon A, Brenner B, Shahzad K, Ruebner M, Isermann B. Kohli S, et al. Blood. 2016 Oct 27;128(17):2153-2164. doi: 10.1182/blood-2016-03-705434. Epub 2016 Sep 2. Blood. 2016. PMID: 27589872 Free article.
p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction.
Kohli S, Hoffmann J, Lochmann F, Markmeyer P, Huebner H, Fahlbusch FB, Al-Dabet MM, Gadi I, Manoharan J, Löttge M, Zenclussen AC, Aharon A, Brenner B, Shahzad K, Ruebner M, Isermann B. Kohli S, et al. Cell Death Dis. 2017 Apr 6;8(4):e2730. doi: 10.1038/cddis.2017.127. Cell Death Dis. 2017. PMID: 28383551 Free PMC article.
Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function.
Madhusudhan T, Wang H, Ghosh S, Dong W, Kumar V, Al-Dabet MM, Manoharan J, Nazir S, Elwakiel A, Bock F, Kohli S, Marquardt A, Sögüt I, Shahzad K, Müller AJ, Esmon CT, Nawroth PP, Reiser J, Chavakis T, Ruf W, Isermann B. Madhusudhan T, et al. Among authors: kohli s. Blood. 2017 Sep 21;130(12):1445-1455. doi: 10.1182/blood-2017-02-767921. Epub 2017 Jul 7. Blood. 2017. PMID: 28687614 Free PMC article.
426 results