Koga N - Search Results

1

Design of complicated all-α protein structures.

Sakuma K, Kobayashi N, Sugiki T, Nagashima T, Fujiwara T, Suzuki K, Kobayashi N, Murata T, Kosugi T, Tatsumi-Koga R, Koga N. Sakuma K, et al. Among authors: koga n. Nat Struct Mol Biol. 2024 Feb;31(2):275-282. doi: 10.1038/s41594-023-01147-9. Epub 2024 Jan 4. Nat Struct Mol Biol. 2024. PMID: 38177681

2

Exploration of novel αβ-protein folds through de novo design.

Minami S, Kobayashi N, Sugiki T, Nagashima T, Fujiwara T, Tatsumi-Koga R, Chikenji G, Koga N. Minami S, et al. Among authors: koga n. Nat Struct Mol Biol. 2023 Aug;30(8):1132-1140. doi: 10.1038/s41594-023-01029-0. Epub 2023 Jul 3. Nat Struct Mol Biol. 2023. PMID: 37400653 Free PMC article.

3

Robust folding of a de novo designed ideal protein even with most of the core mutated to valine.

Koga R, Yamamoto M, Kosugi T, Kobayashi N, Sugiki T, Fujiwara T, Koga N. Koga R, et al. Among authors: koga n. Proc Natl Acad Sci U S A. 2020 Dec 8;117(49):31149-31156. doi: 10.1073/pnas.2002120117. Epub 2020 Nov 23. Proc Natl Acad Sci U S A. 2020. PMID: 33229587 Free PMC article.

4

State-Targeting Stabilization of Adenosine A_2A Receptor by Fusing a Custom-Made De Novo Designed α-Helical Protein.

Mitsumoto M, Sugaya K, Kazama K, Nakano R, Kosugi T, Murata T, Koga N. Mitsumoto M, et al. Among authors: koga n. Int J Mol Sci. 2021 Nov 29;22(23):12906. doi: 10.3390/ijms222312906. Int J Mol Sci. 2021. PMID: 34884716 Free PMC article.

5

Principles for designing ideal protein structures.

Koga N, Tatsumi-Koga R, Liu G, Xiao R, Acton TB, Montelione GT, Baker D. Koga N, et al. Nature. 2012 Nov 8;491(7423):222-7. doi: 10.1038/nature11600. Nature. 2012. PMID: 23135467 Free PMC article.

6

Design of allosteric sites into rotary motor V₁-ATPase by restoring lost function of pseudo-active sites.

Kosugi T, Iida T, Tanabe M, Iino R, Koga N. Kosugi T, et al. Among authors: koga n. Nat Chem. 2023 Nov;15(11):1591-1598. doi: 10.1038/s41557-023-01256-4. Epub 2023 Jul 6. Nat Chem. 2023. PMID: 37414880 Free PMC article.

7

Control over overall shape and size in de novo designed proteins.

Lin YR, Koga N, Tatsumi-Koga R, Liu G, Clouser AF, Montelione GT, Baker D. Lin YR, et al. Among authors: koga n. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5478-85. doi: 10.1073/pnas.1509508112. Epub 2015 Sep 22. Proc Natl Acad Sci U S A. 2015. PMID: 26396255 Free PMC article.

8

Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein.

Basak S, Nobrega RP, Tavella D, Deveau LM, Koga N, Tatsumi-Koga R, Baker D, Massi F, Matthews CR. Basak S, et al. Among authors: koga n. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6806-6811. doi: 10.1073/pnas.1818744116. Epub 2019 Mar 15. Proc Natl Acad Sci U S A. 2019. PMID: 30877249 Free PMC article.

9

ShadowR: a novel chromoprotein with reduced non-specific binding and improved expression in living cells.

Murakoshi H, Horiuchi H, Kosugi T, Onda M, Sato A, Koga N, Nabekura J. Murakoshi H, et al. Among authors: koga n. Sci Rep. 2019 Aug 19;9(1):12072. doi: 10.1038/s41598-019-48604-4. Sci Rep. 2019. PMID: 31427680 Free PMC article.

10

Role of backbone strain in de novo design of complex α/β protein structures.

Koga N, Koga R, Liu G, Castellanos J, Montelione GT, Baker D. Koga N, et al. Among authors: koga r. Nat Commun. 2021 Jun 24;12(1):3921. doi: 10.1038/s41467-021-24050-7. Nat Commun. 2021. PMID: 34168113 Free PMC article.

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