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Page 1
Articular cartilage regeneration by activated skeletal stem cells.
Murphy MP, Koepke LS, Lopez MT, Tong X, Ambrosi TH, Gulati GS, Marecic O, Wang Y, Ransom RC, Hoover MY, Steininger H, Zhao L, Walkiewicz MP, Quarto N, Levi B, Wan DC, Weissman IL, Goodman SB, Yang F, Longaker MT, Chan CKF. Murphy MP, et al. Among authors: koepke ls. Nat Med. 2020 Oct;26(10):1583-1592. doi: 10.1038/s41591-020-1013-2. Epub 2020 Aug 17. Nat Med. 2020. PMID: 32807933 Free PMC article.
Isolation and functional assessment of mouse skeletal stem cell lineage.
Gulati GS, Murphy MP, Marecic O, Lopez M, Brewer RE, Koepke LS, Manjunath A, Ransom RC, Salhotra A, Weissman IL, Longaker MT, Chan CKF. Gulati GS, et al. Among authors: koepke ls. Nat Protoc. 2018 Jun;13(6):1294-1309. doi: 10.1038/nprot.2018.041. Epub 2018 May 10. Nat Protoc. 2018. PMID: 29748647 Free PMC article.
Identification of the Human Skeletal Stem Cell.
Chan CKF, Gulati GS, Sinha R, Tompkins JV, Lopez M, Carter AC, Ransom RC, Reinisch A, Wearda T, Murphy M, Brewer RE, Koepke LS, Marecic O, Manjunath A, Seo EY, Leavitt T, Lu WJ, Nguyen A, Conley SD, Salhotra A, Ambrosi TH, Borrelli MR, Siebel T, Chan K, Schallmoser K, Seita J, Sahoo D, Goodnough H, Bishop J, Gardner M, Majeti R, Wan DC, Goodman S, Weissman IL, Chang HY, Longaker MT. Chan CKF, et al. Among authors: koepke ls. Cell. 2018 Sep 20;175(1):43-56.e21. doi: 10.1016/j.cell.2018.07.029. Cell. 2018. PMID: 30241615 Free PMC article.
Geriatric fragility fractures are associated with a human skeletal stem cell defect.
Ambrosi TH, Goodnough LH, Steininger HM, Hoover MY, Kim E, Koepke LS, Marecic O, Zhao L, Seita J, Bishop JA, Gardner MJ, Chan CKF. Ambrosi TH, et al. Among authors: koepke ls. Aging Cell. 2020 Jul;19(7):e13164. doi: 10.1111/acel.13164. Epub 2020 Jun 14. Aging Cell. 2020. PMID: 32537886 Free PMC article.
Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
Ambrosi TH, Sinha R, Steininger HM, Hoover MY, Murphy MP, Koepke LS, Wang Y, Lu WJ, Morri M, Neff NF, Weissman IL, Longaker MT, Chan CK. Ambrosi TH, et al. Among authors: koepke ls. Elife. 2021 Jul 19;10:e66063. doi: 10.7554/eLife.66063. Elife. 2021. PMID: 34280086 Free PMC article.
Aged skeletal stem cells generate an inflammatory degenerative niche.
Ambrosi TH, Marecic O, McArdle A, Sinha R, Gulati GS, Tong X, Wang Y, Steininger HM, Hoover MY, Koepke LS, Murphy MP, Sokol J, Seo EY, Tevlin R, Lopez M, Brewer RE, Mascharak S, Lu L, Ajanaku O, Conley SD, Seita J, Morri M, Neff NF, Sahoo D, Yang F, Weissman IL, Longaker MT, Chan CKF. Ambrosi TH, et al. Among authors: koepke ls. Nature. 2021 Sep;597(7875):256-262. doi: 10.1038/s41586-021-03795-7. Epub 2021 Aug 11. Nature. 2021. PMID: 34381212 Free PMC article.
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration.
Andrew TW, Koepke LS, Wang Y, Lopez M, Steininger H, Struck D, Boyko T, Ambrosi TH, Tong X, Sun Y, Gulati GS, Murphy MP, Marecic O, Telvin R, Schallmoser K, Strunk D, Seita J, Goodman SB, Yang F, Longaker MT, Yang GP, Chan CKF. Andrew TW, et al. Among authors: koepke ls. Nat Commun. 2022 Oct 30;13(1):6491. doi: 10.1038/s41467-022-34063-5. Nat Commun. 2022. PMID: 36310174 Free PMC article.
A Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue.
Zhao L, Lee AS, Sasagawa K, Sokol J, Wang Y, Ransom RC, Zhao X, Ma C, Steininger HM, Koepke LS, Borrelli MR, Brewer RE, Lee LLY, Huang X, Ambrosi TH, Sinha R, Hoover MY, Seita J, Weissman IL, Wu JC, Wan DC, Xiao J, Longaker MT, Nguyen PK, Chan CKF. Zhao L, et al. Among authors: koepke ls. Arterioscler Thromb Vasc Biol. 2023 Jul;43(7):1262-1277. doi: 10.1161/ATVBAHA.122.317943. Epub 2023 Apr 13. Arterioscler Thromb Vasc Biol. 2023. PMID: 37051932 Free PMC article.
Purification and functional characterization of novel human skeletal stem cell lineages.
Hoover MY, Ambrosi TH, Steininger HM, Koepke LS, Wang Y, Zhao L, Murphy MP, Alam AA, Arouge EJ, Butler MGK, Takematsu E, Stavitsky SP, Hu S, Sahoo D, Sinha R, Morri M, Neff N, Bishop J, Gardner M, Goodman S, Longaker M, Chan CKF. Hoover MY, et al. Among authors: koepke ls. Nat Protoc. 2023 Jul;18(7):2256-2282. doi: 10.1038/s41596-023-00836-5. Epub 2023 Jun 14. Nat Protoc. 2023. PMID: 37316563 Free PMC article. Review.