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Induced global deletion of glucocorticoid receptor impairs fracture healing.
Rapp AE, Hachemi Y, Kemmler J, Koenen M, Tuckermann J, Ignatius A. Rapp AE, et al. Among authors: koenen m. FASEB J. 2018 Apr;32(4):2235-2245. doi: 10.1096/fj.201700459RR. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29217668 Free PMC article.
Collectively, our data show that the absence of the GR significantly impairs fracture healing associated with a defective cartilage-to-bone transition, underscoring an important role of GCs during fracture healing.-Rapp, A. E., Hachemi, Y., Kemmler, J., Koenen, M., …
Collectively, our data show that the absence of the GR significantly impairs fracture healing associated with a defective cartilage-to-bone …
A miR-29a-driven negative feedback loop regulates peripheral glucocorticoid receptor signaling.
Glantschnig C, Koenen M, Gil-Lozano M, Karbiener M, Pickrahn I, Williams-Dautovich J, Patel R, Cummins CL, Giroud M, Hartleben G, Vogl E, Blüher M, Tuckermann J, Uhlenhaut H, Herzig S, Scheideler M. Glantschnig C, et al. Among authors: koenen m. FASEB J. 2019 May;33(5):5924-5941. doi: 10.1096/fj.201801385RR. Epub 2019 Feb 11. FASEB J. 2019. PMID: 30742779
For the first time, we elucidate a microRNA-related mechanism that might contribute to GR dysregulation and resistance in peripheral tissues.-Glantschnig, C., Koenen, M., Gil-Lozano, M., Karbiener, M., Pickrahn, I., Williams-Dautovich, J., Patel, R., C …
For the first time, we elucidate a microRNA-related mechanism that might contribute to GR dysregulation and resistance in peripheral tissues …
122 results