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A phase 1 study in healthy participants to characterize the safety and pharmacology of inclacumab, a fully human anti-P-selectin antibody, in development for treatment of sickle cell disease.
Mayer CL, Koeck K, Hottmann M, Redfern A, Davis M, Barth A, Geng X, Hoppe C, Yue P. Mayer CL, et al. Among authors: koeck k. Eur J Clin Pharmacol. 2023 Sep;79(9):1219-1228. doi: 10.1007/s00228-023-03514-3. Epub 2023 Jul 12. Eur J Clin Pharmacol. 2023. PMID: 37436495 Free PMC article. Clinical Trial.
An Integrated Analysis of Dostarlimab Immunogenicity.
Lu S, Bowsher RR, Clancy A, Rosen A, Zhang M, Yang Y, Koeck K, Gao M, Potocka E, Guo W, Jen KY, Im E, Milton A. Lu S, et al. Among authors: koeck k. AAPS J. 2021 Jul 29;23(5):96. doi: 10.1208/s12248-021-00624-7. AAPS J. 2021. PMID: 34324079 Free PMC article. Clinical Trial.
Spider Silk for Tissue Engineering Applications.
Salehi S, Koeck K, Scheibel T. Salehi S, et al. Among authors: koeck k. Molecules. 2020 Feb 8;25(3):737. doi: 10.3390/molecules25030737. Molecules. 2020. PMID: 32046280 Free PMC article. Review.
Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model.
Grossauer S, Koeck K, Murphy NE, Meyers ID, Daynac M, Truffaux N, Truong AY, Nicolaides TP, McMahon M, Berger MS, Phillips JJ, James CD, Petritsch CK. Grossauer S, et al. Among authors: koeck k. Oncotarget. 2016 Nov 15;7(46):75839-75853. doi: 10.18632/oncotarget.12419. Oncotarget. 2016. PMID: 27713119 Free PMC article.
Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro.
Sternberg K, Gratz M, Koeck K, Mostertz J, Begunk R, Loebler M, Semmling B, Seidlitz A, Hildebrandt P, Homuth G, Grabow N, Tuemmler C, Weitschies W, Schmitz KP, Kroemer HK. Sternberg K, et al. Among authors: koeck k. J Biomed Mater Res B Appl Biomater. 2012 Jan;100(1):41-50. doi: 10.1002/jbm.b.31918. Epub 2011 Nov 24. J Biomed Mater Res B Appl Biomater. 2012. PMID: 22114061