Koczor CA - Search Results

1

NAD⁺ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells.

Li J, M Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, Beiser A, Andrews JF, Sun M, Koczor CA, Clark J, Hayat F, Makarov MV, Wilk A, Yates NA, Migaud ME, Sobol RW. Li J, et al. Among authors: koczor ca. NAR Cancer. 2021 Nov 17;3(4):zcab044. doi: 10.1093/narcan/zcab044. eCollection 2021 Dec. NAR Cancer. 2021. PMID: 34806016 Free PMC article.

2

NAD⁺-mediated regulation of mammalian base excision repair.

Saville KM, Clark J, Wilk A, Rogers GD, Andrews JF, Koczor CA, Sobol RW. Saville KM, et al. Among authors: koczor ca. DNA Repair (Amst). 2020 Sep;93:102930. doi: 10.1016/j.dnarep.2020.102930. DNA Repair (Amst). 2020. PMID: 33087267 Free PMC article. Review.

3

Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD⁺/SIRT6 axis.

Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW. Koczor CA, et al. Cell Rep. 2021 Nov 2;37(5):109917. doi: 10.1016/j.celrep.2021.109917. Cell Rep. 2021. PMID: 34731617 Free PMC article.

4

Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD⁺ Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase.

Li J, Koczor CA, Saville KM, Hayat F, Beiser A, McClellan S, Migaud ME, Sobol RW. Li J, et al. Among authors: koczor ca. Cancers (Basel). 2022 Jul 22;14(15):3572. doi: 10.3390/cancers14153572. Cancers (Basel). 2022. PMID: 35892832 Free PMC article.

5

Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens.

Koczor CA, Haider AJ, Saville KM, Li J, Andrews JF, Beiser AV, Sobol RW. Koczor CA, et al. Cancers (Basel). 2022 Jul 28;14(15):3676. doi: 10.3390/cancers14153676. Cancers (Basel). 2022. PMID: 35954352 Free PMC article.

6

Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress.

Fang Q, Andrews J, Sharma N, Wilk A, Clark J, Slyskova J, Koczor CA, Lans H, Prakash A, Sobol RW. Fang Q, et al. Among authors: koczor ca. Nucleic Acids Res. 2019 Jul 9;47(12):6269-6286. doi: 10.1093/nar/gkz293. Nucleic Acids Res. 2019. PMID: 31287140 Free PMC article.

7

Mitochondrial DNA damage initiates a cell cycle arrest by a Chk2-associated mechanism in mammalian cells.

Koczor CA, Shokolenko IN, Boyd AK, Balk SP, Wilson GL, LeDoux SP. Koczor CA, et al. J Biol Chem. 2009 Dec 25;284(52):36191-36201. doi: 10.1074/jbc.M109.036020. Epub 2009 Oct 19. J Biol Chem. 2009. PMID: 19840931 Free PMC article.

8

Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction.

Koczor CA, Snyder JW, Shokolenko IN, Dobson AW, Wilson GL, Ledoux SP. Koczor CA, et al. Methods Mol Biol. 2009;554:233-49. doi: 10.1007/978-1-59745-521-3_15. Methods Mol Biol. 2009. PMID: 19513678

9

Mitochondrial matrix P53 sensitizes cells to oxidative stress.

Koczor CA, Torres RA, Fields EJ, Boyd A, Lewis W. Koczor CA, et al. Mitochondrion. 2013 Jul;13(4):277-81. doi: 10.1016/j.mito.2013.03.001. Epub 2013 Mar 14. Mitochondrion. 2013. PMID: 23499753 Free PMC article.

10

Thymidine kinase and mtDNA depletion in human cardiomyopathy: epigenetic and translational evidence for energy starvation.

Koczor CA, Torres RA, Fields EJ, Boyd A, He S, Patel N, Lee EK, Samarel AM, Lewis W. Koczor CA, et al. Physiol Genomics. 2013 Jul 15;45(14):590-6. doi: 10.1152/physiolgenomics.00014.2013. Epub 2013 May 21. Physiol Genomics. 2013. PMID: 23695887 Free PMC article.

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