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Identification of the metabolites of ivermectin in humans.
Tipthara P, Kobylinski KC, Godejohann M, Hanboonkunupakarn B, Roth A, Adams JH, White NJ, Jittamala P, Day NPJ, Tarning J. Tipthara P, et al. Among authors: kobylinski kc. Pharmacol Res Perspect. 2021 Feb;9(1):e00712. doi: 10.1002/prp2.712. Pharmacol Res Perspect. 2021. PMID: 33497030 Free PMC article. Clinical Trial.
Promising approach to reducing Malaria transmission by ivermectin: Sporontocidal effect against Plasmodium vivax in the South American vectors Anopheles aquasalis and Anopheles darlingi.
Pinilla YT, C P Lopes S, S Sampaio V, Andrade FS, Melo GC, Orfanó AS, Secundino NFC, Guerra MGVB, Lacerda MVG, Kobylinski KC, Escobedo-Vargas KS, López-Sifuentes VM, Stoops CA, Baldeviano GC, Tarning J, Vasquez GM, Pimenta PFP, Monteiro WM. Pinilla YT, et al. Among authors: kobylinski kc. PLoS Negl Trop Dis. 2018 Feb 14;12(2):e0006221. doi: 10.1371/journal.pntd.0006221. eCollection 2018 Feb. PLoS Negl Trop Dis. 2018. PMID: 29444080 Free PMC article.
Safety, Pharmacokinetics, and Mosquito-Lethal Effects of Ivermectin in Combination With Dihydroartemisinin-Piperaquine and Primaquine in Healthy Adult Thai Subjects.
Kobylinski KC, Jittamala P, Hanboonkunupakarn B, Pukrittayakamee S, Pantuwatana K, Phasomkusolsil S, Davidson SA, Winterberg M, Hoglund RM, Mukaka M, van der Pluijm RW, Dondorp A, Day NPJ, White NJ, Tarning J. Kobylinski KC, et al. Clin Pharmacol Ther. 2020 May;107(5):1221-1230. doi: 10.1002/cpt.1716. Epub 2019 Dec 27. Clin Pharmacol Ther. 2020. PMID: 31697848 Free PMC article.
Safety, Pharmacokinetics, and Activity of High-Dose Ivermectin and Chloroquine against the Liver Stage of Plasmodium cynomolgi Infection in Rhesus Macaques.
Vanachayangkul P, Im-Erbsin R, Tungtaeng A, Kodchakorn C, Roth A, Adams J, Chaisatit C, Saingam P, Sciotti RJ, Reichard GA, Nolan CK, Pybus BS, Black CC, Lugo-Roman LA, Wegner MD, Smith PL, Wojnarski M, Vesely BA, Kobylinski KC. Vanachayangkul P, et al. Among authors: kobylinski kc. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e00741-20. doi: 10.1128/AAC.00741-20. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32660993 Free PMC article.
A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?
Jittamala P, Monteiro W, Smit MR, Pedrique B, Specht S, Chaccour CJ, Dard C, Del Giudice P, Khieu V, Maruani A, Failoc-Rojas VE, Sáez-de-Ocariz M, Soriano-Arandes A, Piquero-Casals J, Faisant A, Brenier-Pinchart MP, Wimmersberger D, Coulibaly JT, Keiser J, Boralevi F, Sokana O, Marks M, Engelman D, Romani L, Steer AC, von Seidlein L, White NJ, Harriss E, Stepniewska K, Humphreys GS, Kennon K, Guerin PJ, Kobylinski KC. Jittamala P, et al. Among authors: kobylinski kc. PLoS Negl Trop Dis. 2021 Mar 17;15(3):e0009144. doi: 10.1371/journal.pntd.0009144. eCollection 2021 Mar. PLoS Negl Trop Dis. 2021. PMID: 33730099 Free PMC article.
Ivermectin metabolites reduce Anopheles survival.
Kobylinski KC, Tipthara P, Wamaket N, Chainarin S, Kullasakboonsri R, Sriwichai P, Phasomkusolsil S, Hanboonkunupakarn B, Jittamala P, Gemmell R, Boyle J, Wrigley S, Steele J, White NJ, Tarning J. Kobylinski KC, et al. Sci Rep. 2023 May 19;13(1):8131. doi: 10.1038/s41598-023-34719-2. Sci Rep. 2023. PMID: 37208382 Free PMC article.
37 results