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Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-α-MSH and setmelanotide.
Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Bürger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Kühnen P, Kobilka BK, Scheerer P. Heyder NA, et al. Among authors: kobilka bk. Cell Res. 2021 Nov;31(11):1176-1189. doi: 10.1038/s41422-021-00569-8. Epub 2021 Sep 24. Cell Res. 2021. PMID: 34561620 Free PMC article.
The dynamic process of β(2)-adrenergic receptor activation.
Nygaard R, Zou Y, Dror RO, Mildorf TJ, Arlow DH, Manglik A, Pan AC, Liu CW, Fung JJ, Bokoch MP, Thian FS, Kobilka TS, Shaw DE, Mueller L, Prosser RS, Kobilka BK. Nygaard R, et al. Among authors: kobilka ts, kobilka bk. Cell. 2013 Jan 31;152(3):532-42. doi: 10.1016/j.cell.2013.01.008. Cell. 2013. PMID: 23374348 Free PMC article.
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling.
Manglik A, Kim TH, Masureel M, Altenbach C, Yang Z, Hilger D, Lerch MT, Kobilka TS, Thian FS, Hubbell WL, Prosser RS, Kobilka BK. Manglik A, et al. Among authors: kobilka ts, kobilka bk. Cell. 2015 May 21;161(5):1101-1111. doi: 10.1016/j.cell.2015.04.043. Epub 2015 May 14. Cell. 2015. PMID: 25981665 Free PMC article.
Structure and dynamics of GPCR signaling complexes.
Hilger D, Masureel M, Kobilka BK. Hilger D, et al. Among authors: kobilka bk. Nat Struct Mol Biol. 2018 Jan;25(1):4-12. doi: 10.1038/s41594-017-0011-7. Epub 2018 Jan 8. Nat Struct Mol Biol. 2018. PMID: 29323277 Free PMC article. Review.
Structure of the µ-opioid receptor-Gi protein complex.
Koehl A, Hu H, Maeda S, Zhang Y, Qu Q, Paggi JM, Latorraca NR, Hilger D, Dawson R, Matile H, Schertler GFX, Granier S, Weis WI, Dror RO, Manglik A, Skiniotis G, Kobilka BK. Koehl A, et al. Among authors: kobilka bk. Nature. 2018 Jun;558(7711):547-552. doi: 10.1038/s41586-018-0219-7. Epub 2018 Jun 13. Nature. 2018. PMID: 29899455 Free PMC article.
Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.
Krishna Kumar K, Shalev-Benami M, Robertson MJ, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, Skiniotis G. Krishna Kumar K, et al. Among authors: kobilka bk. Cell. 2019 Jan 24;176(3):448-458.e12. doi: 10.1016/j.cell.2018.11.040. Epub 2019 Jan 10. Cell. 2019. PMID: 30639101 Free PMC article.
Assembly of a GPCR-G Protein Complex.
Du Y, Duc NM, Rasmussen SGF, Hilger D, Kubiak X, Wang L, Bohon J, Kim HR, Wegrecki M, Asuru A, Jeong KM, Lee J, Chance MR, Lodowski DT, Kobilka BK, Chung KY. Du Y, et al. Among authors: kobilka bk. Cell. 2019 May 16;177(5):1232-1242.e11. doi: 10.1016/j.cell.2019.04.022. Epub 2019 May 9. Cell. 2019. PMID: 31080064 Free PMC article.
348 results