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NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding.
Levine DC, Kuo HY, Hong HK, Cedernaes J, Hepler C, Wright AG, Sommars MA, Kobayashi Y, Marcheva B, Gao P, Ilkayeva OR, Omura C, Ramsey KM, Newgard CB, Barish GD, Peek CB, Chandel NS, Mrksich M, Bass J. Levine DC, et al. Among authors: kobayashi y. Nat Metab. 2021 Dec;3(12):1621-1632. doi: 10.1038/s42255-021-00498-1. Epub 2021 Dec 13. Nat Metab. 2021. PMID: 34903884 Free PMC article.
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.
Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva B, Hong HK, Chong JL, Buhr ED, Lee C, Takahashi JS, Imai S, Bass J. Ramsey KM, et al. Among authors: kobayashi y. Science. 2009 May 1;324(5927):651-4. doi: 10.1126/science.1171641. Epub 2009 Mar 19. Science. 2009. PMID: 19299583 Free PMC article.
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J. Marcheva B, et al. Among authors: kobayashi y. Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253. Nature. 2010. PMID: 20562852 Free PMC article.
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.
Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J. Fenner D, et al. Among authors: kobayashi y. J Biol Chem. 2011 Nov 11;286(45):39560-72. doi: 10.1074/jbc.M111.269100. Epub 2011 Sep 15. J Biol Chem. 2011. PMID: 21921030 Free PMC article.
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J. Peek CB, et al. Among authors: kobayashi y. Science. 2013 Nov 1;342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19. Science. 2013. PMID: 24051248 Free PMC article.
Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron.
Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Cedernaes J, et al. Among authors: kobayashi y. Cell Metab. 2019 May 7;29(5):1078-1091.e5. doi: 10.1016/j.cmet.2019.01.023. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827863 Free PMC article.
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