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Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway.
Wang XQ, Mao LJ, Fang QH, Kobayashi T, Kim HJ, Sugiura H, Kawasaki S, Togo S, Kamio K, Liu X, Rennard SI. Wang XQ, et al. Among authors: kobayashi t. Prostaglandins Other Lipid Mediat. 2014 Jan;108:23-30. doi: 10.1016/j.prostaglandins.2014.02.002. Epub 2014 Mar 5. Prostaglandins Other Lipid Mediat. 2014. PMID: 24614064
Prostacyclin analogs inhibit fibroblast migration.
Kohyama T, Liu X, Kim HJ, Kobayashi T, Ertl RF, Wen FQ, Takizawa H, Rennard SI. Kohyama T, et al. Among authors: kobayashi t. Am J Physiol Lung Cell Mol Physiol. 2002 Aug;283(2):L428-32. doi: 10.1152/ajplung.00432.2001. Am J Physiol Lung Cell Mol Physiol. 2002. PMID: 12114205 Free article.
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