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Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology.
Tsujikawa K, Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y, Ishigaki S, Hashizume A, Miyatake S, Mitsuhashi S, Miyazaki Y, Kataoka M, Jiayi L, Yasui K, Kuru S, Koike H, Kobayashi K, Sahara N, Ozaki N, Yoshida M, Kakita A, Saito Y, Iwasaki Y, Miyashita A, Iwatsubo T; Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI); Ikeuchi T; Japanese Longitudinal Biomarker Study in PSP and CBD (JALPAC) Consortium; Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M. Tsujikawa K, et al. Among authors: kobayashi k. Sci Adv. 2022 May 27;8(21):eabm5029. doi: 10.1126/sciadv.abm5029. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613261 Free PMC article.
Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.
Ren Q, Ma M, Yang J, Nonaka R, Yamaguchi A, Ishikawa KI, Kobayashi K, Murayama S, Hwang SH, Saiki S, Akamatsu W, Hattori N, Hammock BD, Hashimoto K. Ren Q, et al. Among authors: kobayashi k. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):E5815-E5823. doi: 10.1073/pnas.1802179115. Epub 2018 May 7. Proc Natl Acad Sci U S A. 2018. PMID: 29735655 Free PMC article.
Hyperglycemia induces skeletal muscle atrophy via a WWP1/KLF15 axis.
Hirata Y, Nomura K, Senga Y, Okada Y, Kobayashi K, Okamoto S, Minokoshi Y, Imamura M, Takeda S, Hosooka T, Ogawa W. Hirata Y, et al. Among authors: kobayashi k. JCI Insight. 2019 Feb 21;4(4):e124952. doi: 10.1172/jci.insight.124952. eCollection 2019 Feb 21. JCI Insight. 2019. PMID: 30830866 Free PMC article.
Dopamine error signal to actively cope with lack of expected reward.
Ishino S, Kamada T, Sarpong GA, Kitano J, Tsukasa R, Mukohira H, Sun F, Li Y, Kobayashi K, Naoki H, Oishi N, Ogawa M. Ishino S, et al. Among authors: kobayashi k. Sci Adv. 2023 Mar 10;9(10):eade5420. doi: 10.1126/sciadv.ade5420. Epub 2023 Mar 10. Sci Adv. 2023. PMID: 36897945 Free PMC article.
Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K. Nagai T, et al. Among authors: kobayashi k. Neuron. 2016 Feb 3;89(3):550-65. doi: 10.1016/j.neuron.2015.12.019. Epub 2016 Jan 21. Neuron. 2016. PMID: 26804993 Free article.
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