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A mechanism enhancing macromolecule transport through paracellular spaces induced by Poly-L-Arginine: Poly-L-Arginine induces the internalization of tight junction proteins via clathrin-mediated endocytosis.
Yamaki T, Kamiya Y, Ohtake K, Uchida M, Seki T, Ueda H, Kobayashi J, Morimoto Y, Natsume H. Yamaki T, et al. Among authors: kobayashi j. Pharm Res. 2014 Sep;31(9):2287-96. doi: 10.1007/s11095-014-1324-4. Epub 2014 Mar 5. Pharm Res. 2014. PMID: 24590880
Development of a Transnasal Delivery System for Recombinant Human Growth Hormone (rhGH): Effects of the Concentration and Molecular Weight of Poly-L-arginine on the Nasal Absorption of rhGH in Rats.
Kawashima R, Uchida M, Yamaki T, Ohtake K, Hatanaka T, Uchida H, Ueda H, Kobayashi J, Morimoto Y, Natsume H. Kawashima R, et al. Among authors: kobayashi j. Biol Pharm Bull. 2016;39(3):329-35. doi: 10.1248/bpb.b15-00657. Epub 2015 Dec 25. Biol Pharm Bull. 2016. PMID: 26725528 Free article.
NO-Rich Diet for Lifestyle-Related Diseases.
Kobayashi J, Ohtake K, Uchida H. Kobayashi J, et al. Nutrients. 2015 Jun 17;7(6):4911-37. doi: 10.3390/nu7064911. Nutrients. 2015. PMID: 26091235 Free PMC article. Review.
2,060 results