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Identification of RNF213 as a susceptibility gene for moyamoya disease and its possible role in vascular development.
Liu W, Morito D, Takashima S, Mineharu Y, Kobayashi H, Hitomi T, Hashikata H, Matsuura N, Yamazaki S, Toyoda A, Kikuta K, Takagi Y, Harada KH, Fujiyama A, Herzig R, Krischek B, Zou L, Kim JE, Kitakaze M, Miyamoto S, Nagata K, Hashimoto N, Koizumi A. Liu W, et al. Among authors: kobayashi h. PLoS One. 2011;6(7):e22542. doi: 10.1371/journal.pone.0022542. Epub 2011 Jul 20. PLoS One. 2011. PMID: 21799892 Free PMC article.
Preliminary assessment of ecological exposure of adult residents in Fukushima Prefecture to radioactive cesium through ingestion and inhalation.
Koizumi A, Harada KH, Niisoe T, Adachi A, Fujii Y, Hitomi T, Kobayashi H, Wada Y, Watanabe T, Ishikawa H. Koizumi A, et al. Among authors: kobayashi h. Environ Health Prev Med. 2012 Jul;17(4):292-8. doi: 10.1007/s12199-011-0251-9. Epub 2011 Nov 10. Environ Health Prev Med. 2012. PMID: 22071665 Free PMC article.
P.R4810K, a polymorphism of RNF213, the susceptibility gene for moyamoya disease, is associated with blood pressure.
Koizumi A, Kobayashi H, Liu W, Fujii Y, Senevirathna ST, Nanayakkara S, Okuda H, Hitomi T, Harada KH, Takenaka K, Watanabe T, Shimbo S. Koizumi A, et al. Among authors: kobayashi h. Environ Health Prev Med. 2013 Mar;18(2):121-9. doi: 10.1007/s12199-012-0299-1. Epub 2012 Aug 10. Environ Health Prev Med. 2013. PMID: 22878964 Free PMC article.
Ablation of Rnf213 retards progression of diabetes in the Akita mouse.
Kobayashi H, Yamazaki S, Takashima S, Liu W, Okuda H, Yan J, Fujii Y, Hitomi T, Harada KH, Habu T, Koizumi A. Kobayashi H, et al. Biochem Biophys Res Commun. 2013 Mar 15;432(3):519-25. doi: 10.1016/j.bbrc.2013.02.015. Epub 2013 Feb 11. Biochem Biophys Res Commun. 2013. PMID: 23410753
Downregulation of Securin by the variant RNF213 R4810K (rs112735431, G>A) reduces angiogenic activity of induced pluripotent stem cell-derived vascular endothelial cells from moyamoya patients.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: kobayashi h. Biochem Biophys Res Commun. 2013 Aug 16;438(1):13-9. doi: 10.1016/j.bbrc.2013.07.004. Epub 2013 Jul 12. Biochem Biophys Res Commun. 2013. PMID: 23850618
The moyamoya disease susceptibility variant RNF213 R4810K (rs112735431) induces genomic instability by mitotic abnormality.
Hitomi T, Habu T, Kobayashi H, Okuda H, Harada KH, Osafune K, Taura D, Sone M, Asaka I, Ameku T, Watanabe A, Kasahara T, Sudo T, Shiota F, Hashikata H, Takagi Y, Morito D, Miyamoto S, Nakao K, Koizumi A. Hitomi T, et al. Among authors: kobayashi h. Biochem Biophys Res Commun. 2013 Oct 4;439(4):419-26. doi: 10.1016/j.bbrc.2013.08.067. Epub 2013 Aug 27. Biochem Biophys Res Commun. 2013. PMID: 23994138
9,319 results