Ko H - Search Results

1

Agonists and antagonists for P2 receptors.

Jacobson KA, Costanzi S, Joshi BV, Besada P, Shin DH, Ko H, Ivanov AA, Mamedova L. Jacobson KA, et al. Among authors: ko h. Novartis Found Symp. 2006;276:58-68; discussion 68-72, 107-12, 275-81. doi: 10.1002/9780470032244.ch6. Novartis Found Symp. 2006. PMID: 16805423 Free PMC article. Review.

2

Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor.

Besada P, Shin DH, Costanzi S, Ko H, Mathé C, Gagneron J, Gosselin G, Maddileti S, Harden TK, Jacobson KA. Besada P, et al. Among authors: ko h. J Med Chem. 2006 Sep 7;49(18):5532-43. doi: 10.1021/jm060485n. J Med Chem. 2006. PMID: 16942026 Free PMC article.

3

Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate.

Ivanov AA, Ko H, Cosyn L, Maddileti S, Besada P, Fricks I, Costanzi S, Harden TK, Calenbergh SV, Jacobson KA. Ivanov AA, et al. Among authors: ko h. J Med Chem. 2007 Mar 22;50(6):1166-76. doi: 10.1021/jm060903o. Epub 2007 Feb 16. J Med Chem. 2007. PMID: 17302398 Free PMC article.

4

Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor.

Ko H, Fricks I, Ivanov AA, Harden TK, Jacobson KA. Ko H, et al. J Med Chem. 2007 May 3;50(9):2030-9. doi: 10.1021/jm061222w. Epub 2007 Apr 4. J Med Chem. 2007. PMID: 17407275 Free PMC article.

5

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists.

Ko H, Carter RL, Cosyn L, Petrelli R, de Castro S, Besada P, Zhou Y, Cappellacci L, Franchetti P, Grifantini M, Van Calenbergh S, Harden TK, Jacobson KA. Ko H, et al. Bioorg Med Chem. 2008 Jun 15;16(12):6319-32. doi: 10.1016/j.bmc.2008.05.013. Epub 2008 May 9. Bioorg Med Chem. 2008. PMID: 18514530 Free PMC article.

6

Development of selective agonists and antagonists of P2Y receptors.

Jacobson KA, Ivanov AA, de Castro S, Harden TK, Ko H. Jacobson KA, et al. Among authors: ko h. Purinergic Signal. 2009 Mar;5(1):75-89. doi: 10.1007/s11302-008-9106-2. Epub 2008 Jul 4. Purinergic Signal. 2009. PMID: 18600475 Free PMC article.

7

Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose.

Ko H, Das A, Carter RL, Fricks IP, Zhou Y, Ivanov AA, Melman A, Joshi BV, Kovác P, Hajduch J, Kirk KL, Harden TK, Jacobson KA. Ko H, et al. Bioorg Med Chem. 2009 Jul 15;17(14):5298-311. doi: 10.1016/j.bmc.2009.05.024. Epub 2009 May 15. Bioorg Med Chem. 2009. PMID: 19502066 Free PMC article.

8

Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups.

Das A, Ko H, Burianek LE, Barrett MO, Harden TK, Jacobson KA. Das A, et al. Among authors: ko h. J Med Chem. 2010 Jan 14;53(1):471-80. doi: 10.1021/jm901432g. J Med Chem. 2010. PMID: 19902968 Free PMC article.

9

Pyrimidine ribonucleotides with enhanced selectivity as P2Y(6) receptor agonists: novel 4-alkyloxyimino, (S)-methanocarba, and 5'-triphosphate gamma-ester modifications.

Maruoka H, Barrett MO, Ko H, Tosh DK, Melman A, Burianek LE, Balasubramanian R, Berk B, Costanzi S, Harden TK, Jacobson KA. Maruoka H, et al. Among authors: ko h. J Med Chem. 2010 Jun 10;53(11):4488-501. doi: 10.1021/jm100287t. J Med Chem. 2010. PMID: 20446735 Free PMC article.

10

Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.

Cosyn L, Van Calenbergh S, Joshi BV, Ko H, Carter RL, Kendall Harden T, Jacobson KA. Cosyn L, et al. Among authors: ko h. Bioorg Med Chem Lett. 2009 Jun 1;19(11):3002-5. doi: 10.1016/j.bmcl.2009.04.027. Epub 2009 Apr 14. Bioorg Med Chem Lett. 2009. PMID: 19419868 Free PMC article.

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