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Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.
Stadler D, Kächele M, Jones AN, Hess J, Urban C, Schneider J, Xia Y, Oswald A, Nebioglu F, Bester R, Lasitschka F, Ringelhan M, Ko C, Chou WM, Geerlof A, van de Klundert MA, Wettengel JM, Schirmacher P, Heikenwälder M, Schreiner S, Bartenschlager R, Pichlmair A, Sattler M, Unger K, Protzer U. Stadler D, et al. Among authors: ko c. EMBO Rep. 2021 Jun 4;22(6):e49568. doi: 10.15252/embr.201949568. Epub 2021 May 9. EMBO Rep. 2021. PMID: 33969602 Free PMC article.
Novel viral and host targets to cure hepatitis B.
Ko C, Michler T, Protzer U. Ko C, et al. Curr Opin Virol. 2017 Jun;24:38-45. doi: 10.1016/j.coviro.2017.03.019. Epub 2017 Apr 20. Curr Opin Virol. 2017. PMID: 28433762 Review.
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques.
Burwitz BJ, Wettengel JM, Mück-Häusl MA, Ringelhan M, Ko C, Festag MM, Hammond KB, Northrup M, Bimber BN, Jacob T, Reed JS, Norris R, Park B, Moller-Tank S, Esser K, Greene JM, Wu HL, Abdulhaqq S, Webb G, Sutton WF, Klug A, Swanson T, Legasse AW, Vu TQ, Asokan A, Haigwood NL, Protzer U, Sacha JB. Burwitz BJ, et al. Among authors: ko c. Nat Commun. 2017 Dec 15;8(1):2146. doi: 10.1038/s41467-017-01953-y. Nat Commun. 2017. PMID: 29247188 Free PMC article.
A dual role for SAMHD1 in regulating HBV cccDNA and RT-dependent particle genesis.
Wing PA, Davenne T, Wettengel J, Lai AG, Zhuang X, Chakraborty A, D'Arienzo V, Kramer C, Ko C, Harris JM, Schreiner S, Higgs M, Roessler S, Parish JL, Protzer U, Balfe P, Rehwinkel J, McKeating JA. Wing PA, et al. Among authors: ko c. Life Sci Alliance. 2019 Mar 27;2(2):e201900355. doi: 10.26508/lsa.201900355. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30918010 Free PMC article.
3,134 results