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Metabolic carbonyl reduction of anthracyclines - role in cardiotoxicity and cancer resistance. Reducing enzymes as putative targets for novel cardioprotective and chemosensitizing agents.
Piska K, Koczurkiewicz P, Bucki A, Wójcik-Pszczoła K, Kołaczkowski M, Pękala E. Piska K, et al. Among authors: kolaczkowski m. Invest New Drugs. 2017 Jun;35(3):375-385. doi: 10.1007/s10637-017-0443-2. Epub 2017 Mar 10. Invest New Drugs. 2017. PMID: 28283780 Free PMC article. Review.
Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.
Partyka A, Chłoń-Rzepa G, Wasik A, Jastrzębska-Więsek M, Bucki A, Kołaczkowski M, Satała G, Bojarski AJ, Wesołowska A. Partyka A, et al. Among authors: kolaczkowski m. Bioorg Med Chem. 2015 Jan 1;23(1):212-21. doi: 10.1016/j.bmc.2014.11.008. Epub 2014 Nov 11. Bioorg Med Chem. 2015. PMID: 25435254
New arylpiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and dihydro[1,3]oxazolo[2,3-f]purinedione targeting the serotonin 5-HT1A /5-HT2A /5-HT7 and dopamine D2 receptors.
Chłoń-Rzepa G, Zagórska A, Bucki A, Kołaczkowski M, Pawłowski M, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pękala E, Słoczyńska K. Chłoń-Rzepa G, et al. Among authors: kolaczkowski m. Arch Pharm (Weinheim). 2015 Apr;348(4):242-53. doi: 10.1002/ardp.201500015. Epub 2015 Mar 13. Arch Pharm (Weinheim). 2015. PMID: 25773907
Structure-activity relationships and molecular studies of novel arylpiperazinylalkyl purine-2,4-diones and purine-2,4,8-triones with antidepressant and anxiolytic-like activity.
Zagórska A, Kołaczkowski M, Bucki A, Siwek A, Kazek G, Satała G, Bojarski AJ, Partyka A, Wesołowska A, Pawłowski M. Zagórska A, et al. Among authors: kolaczkowski m. Eur J Med Chem. 2015 Jun 5;97:142-54. doi: 10.1016/j.ejmech.2015.04.046. Epub 2015 May 1. Eur J Med Chem. 2015. PMID: 25965777
Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.
Chłoń-Rzepa G, Bucki A, Kołaczkowski M, Partyka A, Jastrzębska-Więsek M, Satała G, Bojarski AJ, Kalinowska-Tłuścik J, Kazek G, Mordyl B, Głuch-Lutwin M, Wesołowska A. Chłoń-Rzepa G, et al. Among authors: kolaczkowski m. J Enzyme Inhib Med Chem. 2016 Dec;31(6):1048-62. doi: 10.3109/14756366.2015.1088844. Epub 2015 Sep 25. J Enzyme Inhib Med Chem. 2016. PMID: 26406608
137 results