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Cationic amphiphilic drugs induce accumulation of cytolytic lysoglycerophospholipids in the lysosomes of cancer cells and block their recycling into common membrane glycerophospholipids.
Mol Biol Cell. 2024 Mar 1;35(3):ar25. doi: 10.1091/mbc.E23-06-0263. Epub 2023 Dec 20.
Mol Biol Cell. 2024.
PMID: 38117591
Free PMC article.
Unraveling membrane properties at the organelle-level with LipidDyn.
Scrima S, Tiberti M, Campo A, Corcelle-Termeau E, Judith D, Foged MM, Clemmensen KKB, Tooze SA, Jäättelä M, Maeda K, Lambrughi M, Papaleo E.
Scrima S, et al. Among authors: clemmensen kkb.
Comput Struct Biotechnol J. 2022 Jun 30;20:3604-3614. doi: 10.1016/j.csbj.2022.06.054. eCollection 2022.
Comput Struct Biotechnol J. 2022.
PMID: 35860415
Free PMC article.
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Zinc Finger Transcription Factor MZF1-A Specific Regulator of Cancer Invasion.
Brix DM, Bundgaard Clemmensen KK, Kallunki T.
Brix DM, et al. Among authors: bundgaard clemmensen kk.
Cells. 2020 Jan 16;9(1):223. doi: 10.3390/cells9010223.
Cells. 2020.
PMID: 31963147
Free PMC article.
Review.
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Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1.
Tvingsholm SA, Hansen MB, Clemmensen KKB, Brix DM, Rafn B, Frankel LB, Louhimo R, Moreira J, Hautaniemi S, Gromova I, Jäättelä M, Kallunki T.
Tvingsholm SA, et al. Among authors: clemmensen kkb.
Oncogenesis. 2018 Feb 3;7(2):14. doi: 10.1038/s41389-017-0014-6.
Oncogenesis. 2018.
PMID: 29396433
Free PMC article.
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When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.
Brix DM, Clemmensen KK, Kallunki T.
Brix DM, et al. Among authors: clemmensen kk.
Cells. 2014 Jan 27;3(1):53-78. doi: 10.3390/cells3010053.
Cells. 2014.
PMID: 24709902
Free PMC article.
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