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A conformational switch controlling the toxicity of the prion protein.
Frontzek K, Bardelli M, Senatore A, Henzi A, Reimann RR, Bedir S, Marino M, Hussain R, Jurt S, Meisl G, Pedotti M, Mazzola F, Siligardi G, Zerbe O, Losa M, Knowles T, Lakkaraju A, Zhu C, Schwarz P, Hornemann S, Holt MG, Simonelli L, Varani L, Aguzzi A. Frontzek K, et al. Among authors: knowles t. Nat Struct Mol Biol. 2022 Aug;29(8):831-840. doi: 10.1038/s41594-022-00814-7. Epub 2022 Aug 10. Nat Struct Mol Biol. 2022. PMID: 35948768 Free PMC article.
Preventing peptide and protein misbehavior.
Arosio P, Meisl G, Andreasen M, Knowles TP. Arosio P, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5267-8. doi: 10.1073/pnas.1505170112. Epub 2015 Apr 20. Proc Natl Acad Sci U S A. 2015. PMID: 25902542 Free PMC article. No abstract available.
Physical principles of filamentous protein self-assembly kinetics.
Michaels TC, Liu LX, Meisl G, Knowles TP. Michaels TC, et al. Among authors: knowles tp. J Phys Condens Matter. 2017 Apr 20;29(15):153002. doi: 10.1088/1361-648X/aa5f10. Epub 2017 Feb 7. J Phys Condens Matter. 2017. PMID: 28170349
Acceleration of α-synuclein aggregation.
Gaspar R, Meisl G, Buell AK, Young L, Kaminski CF, Knowles TPJ, Sparr E, Linse S. Gaspar R, et al. Amyloid. 2017 Mar;24(sup1):20-21. doi: 10.1080/13506129.2017.1292904. Amyloid. 2017. PMID: 28434341 No abstract available.
Absolute Quantification of Amyloid Propagons by Digital Microfluidics.
Pfammatter M, Andreasen M, Meisl G, Taylor CG, Adamcik J, Bolisetty S, Sánchez-Ferrer A, Klenerman D, Dobson CM, Mezzenga R, Knowles TPJ, Aguzzi A, Hornemann S. Pfammatter M, et al. Anal Chem. 2017 Nov 21;89(22):12306-12313. doi: 10.1021/acs.analchem.7b03279. Epub 2017 Nov 1. Anal Chem. 2017. PMID: 28972786 Free PMC article.
Kinetic Analysis of Amyloid Formation.
Meisl G, Michaels TCT, Linse S, Knowles TPJ. Meisl G, et al. Among authors: knowles tpj. Methods Mol Biol. 2018;1779:181-196. doi: 10.1007/978-1-4939-7816-8_12. Methods Mol Biol. 2018. PMID: 29886534
683 results