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Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-β1-driven fibrotic remodeling in ischemic heart failure.
Garlapati V, Molitor M, Michna T, Harms GS, Finger S, Jung R, Lagrange J, Efentakis P, Wild J, Knorr M, Karbach S, Wild S, Vujacic-Mirski K, Münzel T, Daiber A, Brandt M, Gori T, Milting H, Tenzer S, Ruf W, Wenzel P. Garlapati V, et al. Among authors: knorr m. J Clin Invest. 2023 Feb 15;133(4):e156436. doi: 10.1172/JCI156436. J Clin Invest. 2023. PMID: 36548062 Free PMC article.
Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1.
Schuhmacher S, Wenzel P, Schulz E, Oelze M, Mang C, Kamuf J, Gori T, Jansen T, Knorr M, Karbach S, Hortmann M, Mäthner F, Bhatnagar A, Förstermann U, Li H, Münzel T, Daiber A. Schuhmacher S, et al. Among authors: knorr m. Hypertension. 2010 Apr;55(4):897-904. doi: 10.1161/HYPERTENSIONAHA.109.149542. Epub 2010 Feb 15. Hypertension. 2010. PMID: 20157049 Free PMC article.
Conversion of biliverdin to bilirubin by biliverdin reductase contributes to endothelial cell protection by heme oxygenase-1-evidence for direct and indirect antioxidant actions of bilirubin.
Jansen T, Hortmann M, Oelze M, Opitz B, Steven S, Schell R, Knorr M, Karbach S, Schuhmacher S, Wenzel P, Münzel T, Daiber A. Jansen T, et al. Among authors: knorr m. J Mol Cell Cardiol. 2010 Aug;49(2):186-95. doi: 10.1016/j.yjmcc.2010.04.011. Epub 2010 Apr 27. J Mol Cell Cardiol. 2010. PMID: 20430037
α1AMP-activated protein kinase preserves endothelial function during chronic angiotensin II treatment by limiting Nox2 upregulation.
Schuhmacher S, Foretz M, Knorr M, Jansen T, Hortmann M, Wenzel P, Oelze M, Kleschyov AL, Daiber A, Keaney JF Jr, Wegener G, Lackner K, Münzel T, Viollet B, Schulz E. Schuhmacher S, et al. Among authors: knorr m. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):560-6. doi: 10.1161/ATVBAHA.110.219543. Epub 2011 Jan 4. Arterioscler Thromb Vasc Biol. 2011. PMID: 21205985 Free PMC article.
Nitroglycerin-induced endothelial dysfunction and tolerance involve adverse phosphorylation and S-Glutathionylation of endothelial nitric oxide synthase: beneficial effects of therapy with the AT1 receptor blocker telmisartan.
Knorr M, Hausding M, Kröller-Schuhmacher S, Steven S, Oelze M, Heeren T, Scholz A, Gori T, Wenzel P, Schulz E, Daiber A, Münzel T. Knorr M, et al. Arterioscler Thromb Vasc Biol. 2011 Oct;31(10):2223-31. doi: 10.1161/ATVBAHA.111.232058. Epub 2011 Jul 14. Arterioscler Thromb Vasc Biol. 2011. PMID: 21757654
Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy.
Schuhmacher S, Oelze M, Bollmann F, Kleinert H, Otto C, Heeren T, Steven S, Hausding M, Knorr M, Pautz A, Reifenberg K, Schulz E, Gori T, Wenzel P, Münzel T, Daiber A. Schuhmacher S, et al. Among authors: knorr m. Diabetes. 2011 Oct;60(10):2608-16. doi: 10.2337/db10-1395. Epub 2011 Aug 15. Diabetes. 2011. PMID: 21844097 Free PMC article.
Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction.
Wenzel P, Knorr M, Kossmann S, Stratmann J, Hausding M, Schuhmacher S, Karbach SH, Schwenk M, Yogev N, Schulz E, Oelze M, Grabbe S, Jonuleit H, Becker C, Daiber A, Waisman A, Münzel T. Wenzel P, et al. Among authors: knorr m. Circulation. 2011 Sep 20;124(12):1370-81. doi: 10.1161/CIRCULATIONAHA.111.034470. Epub 2011 Aug 29. Circulation. 2011. PMID: 21875910
Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression.
Oelze M, Knorr M, Kröller-Schön S, Kossmann S, Gottschlich A, Rümmler R, Schuff A, Daub S, Doppler C, Kleinert H, Gori T, Daiber A, Münzel T. Oelze M, et al. Among authors: knorr m. Eur Heart J. 2013 Nov;34(41):3206-16. doi: 10.1093/eurheartj/ehs100. Epub 2012 May 3. Eur Heart J. 2013. PMID: 22555214
275 results