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Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.
Chopra N, Kannankeril PJ, Yang T, Hlaing T, Holinstat I, Ettensohn K, Pfeifer K, Akin B, Jones LR, Franzini-Armstrong C, Knollmann BC. Chopra N, et al. Among authors: knollmann bc. Circ Res. 2007 Sep 14;101(6):617-26. doi: 10.1161/CIRCRESAHA.107.157552. Epub 2007 Jul 26. Circ Res. 2007. PMID: 17656677
Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.
Hwang HS, Hasdemir C, Laver D, Mehra D, Turhan K, Faggioni M, Yin H, Knollmann BC. Hwang HS, et al. Among authors: knollmann bc. Circ Arrhythm Electrophysiol. 2011 Apr;4(2):128-35. doi: 10.1161/CIRCEP.110.959916. Epub 2011 Jan 26. Circ Arrhythm Electrophysiol. 2011. PMID: 21270101 Free PMC article.
179 results