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Contrasting Nav1.8 Activity in Scn10a-/- Ventricular Myocytes and the Intact Heart.
Stroud DM, Yang T, Bersell K, Kryshtal DO, Nagao S, Shaffer C, Short L, Hall L, Atack TC, Zhang W, Knollmann BC, Baudenbacher F, Roden DM. Stroud DM, et al. Among authors: knollmann bc. J Am Heart Assoc. 2016 Nov 2;5(11):e002946. doi: 10.1161/JAHA.115.002946. J Am Heart Assoc. 2016. PMID: 27806966 Free PMC article.
Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia.
Knollmann BC, Chopra N, Hlaing T, Akin B, Yang T, Ettensohn K, Knollmann BE, Horton KD, Weissman NJ, Holinstat I, Zhang W, Roden DM, Jones LR, Franzini-Armstrong C, Pfeifer K. Knollmann BC, et al. Among authors: knollmann be. J Clin Invest. 2006 Sep;116(9):2510-20. doi: 10.1172/JCI29128. Epub 2006 Aug 24. J Clin Invest. 2006. PMID: 16932808 Free PMC article.
Modest reductions of cardiac calsequestrin increase sarcoplasmic reticulum Ca2+ leak independent of luminal Ca2+ and trigger ventricular arrhythmias in mice.
Chopra N, Kannankeril PJ, Yang T, Hlaing T, Holinstat I, Ettensohn K, Pfeifer K, Akin B, Jones LR, Franzini-Armstrong C, Knollmann BC. Chopra N, et al. Among authors: knollmann bc. Circ Res. 2007 Sep 14;101(6):617-26. doi: 10.1161/CIRCRESAHA.107.157552. Epub 2007 Jul 26. Circ Res. 2007. PMID: 17656677
Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.
Chopra N, Yang T, Asghari P, Moore ED, Huke S, Akin B, Cattolica RA, Perez CF, Hlaing T, Knollmann-Ritschel BE, Jones LR, Pessah IN, Allen PD, Franzini-Armstrong C, Knollmann BC. Chopra N, et al. Among authors: knollmann bc, knollmann ritschel be. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7636-41. doi: 10.1073/pnas.0902919106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383796 Free PMC article.
Striking In vivo phenotype of a disease-associated human SCN5A mutation producing minimal changes in vitro.
Watanabe H, Yang T, Stroud DM, Lowe JS, Harris L, Atack TC, Wang DW, Hipkens SB, Leake B, Hall L, Kupershmidt S, Chopra N, Magnuson MA, Tanabe N, Knollmann BC, George AL Jr, Roden DM. Watanabe H, et al. Among authors: knollmann bc. Circulation. 2011 Aug 30;124(9):1001-11. doi: 10.1161/CIRCULATIONAHA.110.987248. Epub 2011 Aug 8. Circulation. 2011. PMID: 21824921 Free PMC article.
179 results