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Selective oxytocin receptor activation prevents prefrontal circuit dysfunction and social behavioral alterations in response to chronic prefrontal cortex activation in male rats.
Janz P, Knoflach F, Bleicher K, Belli S, Biemans B, Schnider P, Ebeling M, Grundschober C, Benekareddy M. Janz P, et al. Among authors: knoflach f. Front Cell Neurosci. 2023 Dec 7;17:1286552. doi: 10.3389/fncel.2023.1286552. eCollection 2023. Front Cell Neurosci. 2023. PMID: 38145283 Free PMC article.
The molecular basis of drug selectivity for α5 subunit-containing GABAA receptors.
Kasaragod VB, Malinauskas T, Wahid AA, Lengyel J, Knoflach F, Hardwick SW, Jones CF, Chen WN, Lucas X, El Omari K, Chirgadze DY, Aricescu AR, Cecere G, Hernandez MC, Miller PS. Kasaragod VB, et al. Among authors: knoflach f. Nat Struct Mol Biol. 2023 Dec;30(12):1936-1946. doi: 10.1038/s41594-023-01133-1. Epub 2023 Oct 30. Nat Struct Mol Biol. 2023. PMID: 37903907 Free PMC article.
Pharmacological modulation of GABAA receptors.
Knoflach F, Bertrand D. Knoflach F, et al. Curr Opin Pharmacol. 2021 Aug;59:3-10. doi: 10.1016/j.coph.2021.04.003. Epub 2021 May 18. Curr Opin Pharmacol. 2021. PMID: 34020139 Review.
Basmisanil, a highly selective GABAA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man.
Hipp JF, Knoflach F, Comley R, Ballard TM, Honer M, Trube G, Gasser R, Prinssen E, Wallace TL, Rothfuss A, Knust H, Lennon-Chrimes S, Derks M, Bentley D, Squassante L, Nave S, Nöldeke J, Wandel C, Thomas AW, Hernandez MC. Hipp JF, et al. Among authors: knoflach f. Sci Rep. 2021 Apr 8;11(1):7700. doi: 10.1038/s41598-021-87307-7. Sci Rep. 2021. PMID: 33833333 Free PMC article.
mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis.
Costa V, Aigner S, Vukcevic M, Sauter E, Behr K, Ebeling M, Dunkley T, Friedlein A, Zoffmann S, Meyer CA, Knoflach F, Lugert S, Patsch C, Fjeldskaar F, Chicha-Gaudimier L, Kiialainen A, Piraino P, Bedoucha M, Graf M, Jessberger S, Ghosh A, Bischofberger J, Jagasia R. Costa V, et al. Among authors: knoflach f. Cell Rep. 2016 Apr 5;15(1):86-95. doi: 10.1016/j.celrep.2016.02.090. Epub 2016 Mar 24. Cell Rep. 2016. PMID: 27052171 Free article.
57 results